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A sprain is an injury to a ligament; a strain is an injury to a muscle or tendon. ...more »
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A sprain is an injury to a ligament--a stretching or a tearing. One or more ligaments can be injured during a sprain. The severity of the injury will depend on the extent of injury to a single ligament (whether the tear is partial or complete) and the number of ligaments involved. (Source: excerpt from Questions and Answers Sprains and Strains: NIAMS)
A painful injury to a joint caused by a sudden wrenching of its ligaments - (Source - WordNet 2.1)
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