Steroid-resistant asthma, type II: Steroid-resistant asthma is a type of asthma that doesn't respond to steroid treatment. Steroids work by attaching to a particular part of the T-cells which make up the immune system. In type I, the T-cells have sufficient attachment points for the steroids but they are ineffective. In type II, there are insufficient attachment points for the steroids which make them less effective or completely ineffective. Steroid-resistant asthma (like other forms of asthma) involves rapid constriction and inflammation of the airways which makes breathing difficult. More detailed information about the symptoms, causes, and treatments of Steroid-resistant asthma, type II is available below.
There is no cure but avoiding triggers will prevent symptoms developing. Symptoms may be managed through higher doses of steroid-based asthma medication but immunoglobulin therapy may reduce the need for such high doses. Anti-leukotriene drugs may help in some cases. Various alternative therapies are being investigated: cyclosporine, methotrexate, gold, IV gamma globulin, dapsone, and ...more treatments »
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Prognosis for Steroid-resistant asthma, type II: This form of asthma is more difficult to treat and hence is usually more serious. The alternative treatments required often have more side effects than standard asthma treatments using normal levels of steroids.
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