- Peripheral neuropathy:
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Peripheral neuropathy is an abnormal condition in which the peripheral nerves are damaged. The peripheral nerves spread out from the brain and spinal cord, and peripheral neuropathy results in unusual or abnormal sensations of the extremities, especially the feet.
Peripheral neuropathy is a common condition and can result from certain metabolic disorders, infections, malignancy, inflammation, vitamin deficiencies, toxins, inherited conditions, and other abnormal processes. A very common cause of peripheral neuropathy is diabetes. Other causes of peripheral neuropathy include alcoholism, vasculitis, vitamin B deficiency, vitamin E deficiency, chemotherapy, and exposure to certain toxins, such as insecticides, lead, mercury, and arsenic.
Peripheral neuropathy generally develops slowly over a period of months. Symptoms of peripheral neuropathy include a sensation of pain, numbness, tingling, or prickling that begins in the feet. In later stages of peripheral neuropathy, the hands can be affected as well. In some cases, the abnormal sensations can extend to the arms, legs, and trunk. Peripheral neuropathy can also affect the muscles resulting in weakness and atrophy. There are other symptoms that can accompany peripheral neuropathy, depending on the disease, disorder or condition that causing it. For more details about symptoms and complications, see symptoms of peripheral neuropathy.
Diagnosing peripheral neuropathy and its root cause begins with taking a thorough personal and family medical history, including symptoms, and completing a physical examination, including a neurological examination. A neurological exam evaluates the nervous system and such functions as reflexes, sensation, movement, balance, coordination, vision, and hearing.
Tests may include an electromyography (EMG) which tests the nerve and electrical activity of muscles. A nerve conduction test may also be performed to test how fast the nerves transmit impulses.
Making a diagnosis of peripheral neuropathy also includes performing a variety of other tests to help to diagnose the underlying disease, condition or disorder that is causing peripheral neuropathy. A biopsy of a nerve in the ankle may be performed. This involves taking a small sample of the nerve to examine under a microscope.
A diagnosis of peripheral neuropathy and its cause can easily be delayed or missed because symptoms develop very gradually. For information on misdiagnosis, refer to misdiagnosis of peripheral neuropathy.
Treatment of peripheral neuropathy involves diagnosing and treating the underlying disease, disorder or condition. Some conditions can be easily and successfully treated and cured, while others may require more intensive treatment and may not have an optimal prognosis. For more information on treatment, refer to treatment of peripheral neuropathy....more »
A diagnosis of peripheral neuropathy and its cause may be delayed or missed because peripheral neuropathy generally develops very gradually and people with the condition may be unaware of it. Peripheral neuropathy is a symptom of many different conditions, so a thorough medical evaluation is needed to ensure an accurate diagnosis of the reason for peripheral neuropathy. ...more misdiagnosis »
The following medical conditions are some of the possible
causes of Peripheral neuropathy.
There are likely to be other possible causes, so ask your doctor
about your symptoms.
Home medical tests possibly related to Peripheral neuropathy:
Review the causes of these more specific types of Peripheral neuropathy:
Review causes of more specific types of Peripheral neuropathy:
Listed below are some combinations of symptoms associated with Peripheral neuropathy, as listed in our database. Visit the Symptom Checker, to add and remove symptoms and research your condition.
Treatment plans for peripheral neuropathy are individualized depending on the cause, the presence of coexisting diseases, the age of the patient, and other factors. Treatment generally involves a multifaceted plan that addresses the underlying cause and helps to minimize the pain and abnormal sensations of peripheral neuropathy and the risk of developing gangrene and other ...Peripheral neuropathy Treatments
Some of the possible treatments listed in sources for treatment of Peripheral neuropathy may include:
Review further information on Peripheral neuropathy Treatments.
Alternative treatments or home remedies that have been listed as possibly helpful for Peripheral neuropathy may include:
Real-life user stories relating to Peripheral neuropathy:
The following drugs, medications, substances or toxins are some of the possible
causes of Peripheral neuropathy as a symptom.
Always advise your doctor of any medications or treatments you are using,
including prescription, over-the-counter, supplements, herbal or alternative treatments.
When combined, certain drugs, medications, substances or toxins may react causing Peripheral neuropathy as a symptom. Always advise your doctor of any medications or treatments you are using, including prescription, over-the-counter, supplements, herbal or alternative treatments.
Some of the comorbid or associated medical symptoms for Peripheral neuropathy may include these symptoms:
Research the causes of these more general types of symptom:
Research the causes of related medical symptoms such as:
Research the causes of these symptoms that are similar to, or related to, the symptom Peripheral neuropathy:
Read more about causes and Peripheral neuropathy deaths.
Diabetes diagnosis and misdiagnosis (In-Depth Report): Detailed report on diabetes misdiagnoses, rare curable types, and less common diagnostic issues....read full report »
Heart attacks can be undiagnosed: Although the most severe symptoms of heart attack are hard to miss, there are varying degrees of severity. It is altogether too common for people to die from undiagnosed heart...read more »
Heart attacks can be overdiagnosed: Although many people die from heart attacks, there are also many cases where people fear that they have a heart attack, but actually have something milder. Some of the...read more »
Cluster of diseases with difficult diagnosis issues: There is a well-known list of medical conditions that are all somewhat difficult to diagnose, and all can present in a variety of...read more »
Poorly healing leg rashes a classic sign of chronic disease: Recurring leg rashes, or poorly healing leg rashes, are a classic sign of undiagnosed diabetes, particularly of Type 2 diabetes, but...read more »
Leg cramps at night a classic sign: The symptom of having leg muscle cramps, particularly at night, is a classic sign of undiagnosed diabetes. However, there are also various other causes. See causes of leg cramps or misdiagnosis of diabetes....read more »
Obesity-related conditions undiagnosed in children: A variety of conditions are associated with obesity (see obesity), but these tend to be undiagnosed more often in child patients than in adults. Some of the...read more »
Vitamin B12 deficiency under-diagnosed: The condition of Vitamin B12 deficiency is a possible misdiagnosis of various conditions, such as multiple sclerosis (see symptoms of multiple sclerosis). See symptoms of Vitamin B12...read more »
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Research extensive quality ratings and patient safety measures for hospitals, clinics and medical facilities in health specialties related to Peripheral neuropathy:
Rare types of medical conditions and diseases in related medical categories:
Conditions that are commonly undiagnosed in related areas may include:
Other medical conditions listed in the Disease Database as possible
causes of Peripheral neuropathy as a symptom include:
Peripheral neuropathy is a common neurological disorder resulting from damage to the peripheral nerves. It may be caused by diseases of the nerves or as the result of systemic illnesses. (Source: excerpt from NINDS Peripheral Neuropathy Information Page: NINDS)
Peripheral neuropathy is a common neurological disorder resulting from damage to the peripheral... (Source: excerpt from NINDS Peripheral Neuropathy Information Page: NINDS)
Diseases of the peripheral nerves external to the brain and spinal cord, which includes diseases of the nerve roots, ganglia, plexi, autonomic nerves, sensory nerves, and motor nerves.
- (Source - Diseases Database)
The list below shows some of the causes of Peripheral neuropathy mentioned in various sources:
This information refers to the general prevalence and incidence of these diseases, not to how likely they are to be the actual cause of Peripheral neuropathy. Of the 299 causes of Peripheral neuropathy that we have listed, we have the following prevalence/incidence information:
The following list of conditions have 'Peripheral neuropathy' or similar listed as a symptom in our database. This computer-generated list may be inaccurate or incomplete. Always seek prompt professional medical advice about the cause of any symptom.
Select from the following alphabetical view of conditions which include a symptom of Peripheral neuropathy or choose View All.
The following list of medical conditions have Peripheral neuropathy or similar listed as a medical complication in our database. The distinction between a symptom and complication is not always clear, and conditions mentioning this symptom as a complication may also be relevant. This computer-generated list may be inaccurate or incomplete. Always seek prompt professional medical advice about the cause of any symptom.
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This information shows analysis of the list of causes of Peripheral neuropathy based
on whether certain risk factors apply to the patient:
Subtypes of Peripheral neuropathy:
Sensory peripheral neuropathy (1 cause)
Medical Conditions associated with Peripheral neuropathy:
Nerve symptoms (9132 causes), Sensory symptoms (7134 causes), Neurological symptoms (9575 causes), Pain (6458 causes), Sensations (6520 causes), Digestive symptoms (5299 causes), Abdominal symptoms (5930 causes), Brain symptoms (2787 causes), Pancreas symptoms (271 causes), Common symptoms (8589 causes), Body symptoms (5672 causes), Head symptoms (10192 causes), Upper abdominal symptoms (2707 causes), Diabetes-related symptoms (327 causes)
Symptoms related to Peripheral neuropathy:
Tingling fingers (36 causes), Tingling toes (16 causes), Numb toes (21 causes), Numb feet (45 causes), Neuropathy (78 causes), Diabetes mellitus (66 causes), Vitamin B12 deficiency, Subacute combined degeneration of the spinal cord, Intermittent claudictaion, Arterial ischemia, Cervical rib, Pancoast tumour
Doctor-patient articles related to symptoms and diagnosis:
These general medical articles may be of interest:
Medical research papers related to Peripheral neuropathy include:
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