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Diagnostic Tests for Hyperpigmentation

Diagnostic Test list for Hyperpigmentation:

The list of diagnostic tests mentioned in various sources as used in the diagnosis of Hyperpigmentation includes:

  • Physical examination
    • Examine the pigmented skin in area or areas affected and note pigmentation features
    • Blood pressure ( postural lowering of blood pressure with Addison's disease)
    • Examine for signs of Addison's disease such as dehydration; dull grey-brown pigmentation in the mouth (around the molars), hands and in new scars; loss of body hair
    • Examine for signs of systemic disease that may be associated with the cause of the dark skin - e.g. scleroderma, hemochromatosis, polycystic ovarian disease.
  • Blood tests
    • Full blood count and ESR
    • Liver function tests (can diagnose jaundice and liver inflammation due to hemochromatosis)
    • Electrolytes and kidney function tests ( high potassium in Addison's disease; elevated calcium in sarcoidosis)
    • Iron studies ( raised ferritin and transferring saturation in hemochromatosis)
    • Cortisol, ACTH assay, Synacthen stimulation test, adrenal antibodies if suspect Addison's disease
    • Antinuclear, antinucleolar and anticentromere antibodies may be elevated in scleroderma
    • HIV serology if suspect Kaposi's sarcoma
    • Hepatitis serology if jaundice is diagnosed
  • Skin biopsy of localized dark skin lesion - to assist diagnosis.
  • Liver biopsy if suspect hemochromatosis
  • Radiological investigations
    • Chest X-Ray if suspect sarcoidosis
  • Transbronchial biopsy - may be required if suspect sarcoidosis.

Conditions listing medical symptoms: Hyperpigmentation:

The following list of conditions have 'Hyperpigmentation' or similar listed as a symptom in our database. This computer-generated list may be inaccurate or incomplete. Always seek prompt professional medical advice about the cause of any symptom.

Select from the following alphabetical view of conditions which include a symptom of Hyperpigmentation or choose View All.

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Conditions listing medical complications: Hyperpigmentation:

The following list of medical conditions have 'Hyperpigmentation' or similar listed as a medical complication in our database.


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