Glossary for Nail abnormalities
Medical terms related to Nail abnormalities or mentioned in this section include:
- Acroosteolysis neurogenic: A very rare inherited condition characterized mainly by the loss of all sensations - the lose the ability to feel pain, temperature and touch. The loss of sensation generally starts at the toes and fingers and spreads up the limbs and the trunk may also be involved in some cases.
- Alopecia Areata: A condition where hair loss occurs in patches for unknown reasons. Although the condition often disappears within a year, it often reoccurs.
- Alves Castelo dos Santos syndrome: A rare syndrome characterized by hair, eye, skin and spinal abnormalities.
- Anonychia onychodystrophy brachydactyly type b: A rare, dominantly inherited disorder characterized abnormal or absent nails, permanently flexed fingers and a broad, finger-like thumb.
- Anonychia-onychodystrophy with brachydactyly type B and ectrodactyly: A rare, dominantly inherited disorder characterized abnormal or absent nails, missing fingers, permanently flexed fingers and a broad, finger-like thumb.
- Aplasia/hypoplasia of pelvis, femur, fibula, and ulna with abnormal digits and nails: A rare syndrome characterized by the underdevelopment or absence of the pelvis, thigh bone, shin bone and ulna (forearm bone) as well as digital and nail abnormalities.
- Arm symptoms: Symptoms affecting the arm
- Bacterial diseases: Diseases caused by a bacterial infection
- Bacterial endocarditis: Infection and inflammation of the inner layers of the heart, most commonly the valves cause by bacteria.
- Beau's lines: Beau's lines are grooves or depressions that run across the nail.
- Brachydactyly, type A5, nail dysplasia: A rare digital anomaly where the middle bones of the second to fifth fingers are missing and the nails are abnormal.
- Bullous dystrophy, macular type: A rare condition characterized by loss of scalp hair, increased skin pigmentation, small head, mental retardation, short stature and blisters. The blisters do not form necessarily on skin that has suffered trauma but occurs spontaneously.
- Cataract and congenital ichthyosis: A rare syndrome characterized by the presence of cataracts and a dry, scaly skin condition (ichthyosis) at birth or soon after.
- Christianson Fourie syndrome: A very rare syndrome characterized mainly by hair and nail abnormalities.
- Chromosome 19q13.11 Deletion syndrome: A rare genetic syndrome involving features such as poor fetal growth, reduced fetal activity, developmental problems and various other physical symptoms.
- Chromosome 8, monosomy 8p: A rare chromosomal disorder involving deletion of genetic material from the short arm (p) of chromosome 8 resulting in various abnormalities. The type and severity of symptoms varies depending on the amount and exact location of the genetic material that is deleted.
- Cote-Katsantoni syndrome: A rare condition characterized by osteosclerosis, atrial septal defect, malabsorption, neutropenia, ectodermal dysplasia, growth retardation and mental retardation.
- Crohn's disease: Crohn's disease causes inflammation of the digestive system. It is one of a group of diseases called inflammatory bowel disease. The disease can affect any area from the mouth to the anus. It often affects the lower part of the small intestine called the ileum.
- Darier disease: A slowly progressing inherited skin disorder characterized by small brownish warty bumps and nail abnormalities. The skin disorder because the skin cells are not held together properly.
- Deafness onychodystrophy dominant form: A rare dominantly inherited disorder characterized by deafness from birth, deformed nails and
- Del(1) (23-q25): A very rare chromosomal disorder where a portion of the long arm (23q-q25) of chromosome one is missing.
- Deletion 8p: A rare chromosomal disorder involving deletion of genetic material from the short arm (p) of chromosome 8 resulting in various abnormalities. The type and severity of symptoms varies depending on the amount and exact location of the genetic material that is deleted.
- Dilantin -- Teratogenic Agent: There is strong evidence to indicate that the use of Dilantin (anti-seizure medication) during pregnancy may cause a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the level of exposure and the stage of pregnancy that the exposure occurred at.
- Ectodermal dysplasia: A group of rare inherited conditions which affect the ectodermal skin layer which includes the skin, hair, teeth and nails.
- Ectodermal dysplasia anhidrotic: A rare inherited condition involving skin, hair, teeth and nail abnormalities. The condition is characterized by the absence of sweat and sebaceous glands, underdeveloped hair and teeth, characteristic face and other physical deformities.
- Ectodermal dysplasia trichoodontoonychial type: A rare syndrome characterized by nail, tooth and hair abnormalities.
- Ectodermal dysplasia, Margarita type: A rare genetic disorder characterized by mental retardation, webbed digits, cleft lip, cleft palate, sparse hair, reduced sweating and teeth abnormalities. Progressive loss of scalp hair usually results in baldness by adulthood.
- Ectrodactyly -- Ectodermal Dysplasia -- Cleft Lip/Palate Syndrome, Type 1: EEC (Ectrodactyly, ectodermal dysplasia, cleft lip/palate) is a rare inherited condition characterized by split hand and foot deformities of variable severity, cleft lip or palate and teeth and hair anomalies. There are two main types of EEC which differ in the origin of the genetic defect. Type 1 is caused by a defect on chromosome 7q11. The severity and type of symptoms and deformities is highly variable.
- Ectrodactyly -- Ectodermal Dysplasia -- Cleft Lip/Palate Syndrome, Type 3: EEC (Ectrodactyly, ectodermal dysplasia, cleft lip/palate) is a rare inherited condition characterized by split hand and foot deformities of variable severity, cleft lip or palate and teeth and hair anomalies. There are two main types of EEC which differ in the origin of the genetic defect. Type 3 is caused by a defect on chromosome 3q27. The severity and type of symptoms and deformities is highly variable.
- Eczema: Skin rash usually from allergic causes.
- Epidermolysis bullosa, dermolytic: A rare genetic syndrome characterized by fragile skin which blisters easily due to defective skin collagen. The mucosal lining of the mouth and even intestines may be effected in severe cases.
- Erythroderma: Condition with thickening and flaking skin
- Factitious syndromes: A disorder that a person believes they have that however does not exist
- Fernhoff-Blackston-Oakley syndrome: A very rare syndrome characterized mainly by retarded fetal growth and jaw anomaly as well as various other abnormalities.
- Finger symptoms: Symptoms affecting any fingers
- Fingernail symptoms: Symptoms affecting the fingernails
- Foot symptoms: Symptoms affecting one or both feet
- Freire-Maia odontotrichomelic syndrome: A rare syndrome characterized by tooth, hair and limb abnormalities.
- Freire-Maia syndrome: An extremely rare syndrome characterized by tooth, hair and limb abnormalities. The abnormalities can be quite severe in some cases. The parents may have been related in the reported cases.
- Fryns Syndrome: A rare genetic disorder characterized by diaphragmatic abnormalities, coarse face and abnormal growth or development of ends of fingers and toes.
- Fungal infections: Symptoms from various fungal infections
- Fungal symptoms: Symptoms from various fungal infections
- Goldblatt-Wallis syndrome: A very rare syndrome characterized by mental retardation and an abnormally placed urethral opening in males.
- Halal Setton Wang syndrome: A very rare syndrome characterized mainly by eye, teeth, nail and skin abnormalities.
- Hand symptoms: Symptoms affecting the hand
- Hematoma: Local collection of clotted blood
- Hidrotic ectodermal dysplasia, type Christianson-Fourie: A very rare syndrome characterized mainly by hair and nail abnormalities.
- Hyperthyroidism: The excessive activity of the thyroid gland
- Hypothyroidism: The decreased activity of the thyroid gland
- Ichthyosis -- alopecia -- eclabion -- ectropion -- mental retardation: A very rare syndrome characterized mainly by scaly skin, hair loss, mental retardation and outwardly turned eyelids and lips.
- Ichthyosis and male hypogonadism: A very rare syndrome characterized mainly by scaly skin and insufficient hormone production by the male gonads.
- Ichthyosis male hypogonadism: A very rare syndrome characterized mainly by scaly skin and insufficient hormone production by the male gonads.
- Incontinentia Pigmenti: A rare genetic skin pigmentation disorder characterized by eye, teeth, bone, nail and hair malformations as well as central nervous abnormalities and mental deficiency.
- Infection: Infections as a symptom.
- Injury: Any damage inflicted in the body
- Iron deficiency: When there is a deficiency of iron in the body
- Iron deficiency anemia: Iron-deficiency anemia is a blood condition characterized by low levels of iron in the body which leads to a reduction in the number of red blood cells.
- Jadassohn-Lewandowsky syndrome: A rare, inherited disorder characterized by thickening of nails, white patches on mouth and anus(leukoplakia) and thickened hard skin on soles and palms.
- Kaplan-Plauchu-Fitch syndrome: A very rare syndrome characterized mainly by cone-shaped skull, short stature, deafness and various facial and digital abnormalities.
- Keratosis focal -- palmoplantar, gingival: A rare syndrome characterized mainly by thickened skin on the soles and palms in areas that are under the most trauma e.g. weight-bearing part of sole. The gums also have thickened growths.
- Keratosis palmoplantar periodontopathy: A very rare inherited condition characterized by dry scaly patches on the skin of the palms and soles, gum and teeth problems and frequent skin infections.
- Keratosis palmoplantaris papulosa: A rare condition involving thickening of the skin on the palms and soles
- Kidney disease: Reduced kidney function from various causes.
- Kidney symptoms: Symptoms affecting one or both kidneys.
- Kumar levick syndrome: A rare syndrome characterized by missing or abnormal nails, missing fingers, permanently bent fingers and a finger-like thumb.
- Leg symptoms: Symptoms affecting the leg
- Lichen planus: Skin rash
- Limb symptoms: Symptoms affecting the limbs
- Limb-mammary syndrome: A rare syndrome characterized by abnormalities of the hand and/or foot as well as absent or underdeveloped mammary glands and nipples. The severity of the deformity is variable. Tooth, nail and sweat gland abnormalities may also be present.
- Liver conditions: Any condition that affects the liver
- Liver symptoms: Symptoms affecting the liver
- Lower leg symptoms: Symptoms affecting the lower legs, calves and shins.
- Lung conditions: Various conditions affecting the lungs or related airways.
- Lung symptoms: Symptoms affecting one or both lungs.
- Lymphedema -- ptosis: A very rare syndrome characterized mainly by lymphedema (lymphatic obstruction) in the legs and droopy eyelids.
- Manouvrier syndrome: A very rare syndrome characterized mainly by the failure of the lungs to develop fully, heart defects and thumb abnormalities.
- Melanoma: Melanoma is the most dangerous type of skin cancer. It is the leading cause of death from skin disease. It involves cells called melanocytes, which produce a skin pigment called melanin. Melanin is responsible for skin and hair color.
- Meleda Disease: A very rare inherited skin disorder primarily involving dry thick skin patches that develop on the palms of hands and soles of feet. The type and severity of symptoms is variable.
- Mental retardation, Buenos Aires type: A very rare syndrome characterized mainly by mental retardation, physical retardation, unusual facial appearance and heart and kidney defects.
- Moloney syndrome: A very rare syndrome characterized mainly by wasting of the choroids in the eye and sparse, fine hair. The choroid is a layer of blood vessels that lies between the retina and the sclera and delivers blood to the back of the eye.
- Nail abnormalities in children: Nail abnormalities in children are any type of deformity or irregularity in a child's nails.
- Nail abnormality: An abnormality of the finger and/or toe nails.
- Nail conditions: Any condition that affects the nail
- Nail dysplasia, isolated congenital: A rare genetic disorder characterized by abnormal nail development which is usually evident at birth or soon after.
- Nail symptoms: Symptoms affecting the fingernails or toenails
- OLEDAID: A rare syndrome characterized mainly by a weak immuned system, bone problems, lymphoedema and hair, teeth and nail abnormalities. Death usually occurs during the first few years of life due to overwhelming infections.
- Odonto-tricho-ungual-digito-palmarn syndrome: A rare syndrome characterized mainly by the presence of teeth at birth, hair loss and hand and foot malformations.
- Odontoonychodermal dysplasia: A very rare syndrome characterized mainly by tooth, nail and skin abnormalities.
- Onychodystrophy and anonychia with type B brachydactyly and ectrodactyly: A rare, dominantly inherited disorder characterized abnormal or absent nails, missing fingers, permanently flexed fingers and a broad, finger-like thumb.
- Onychotrichodysplasia and neutropenia: A very rare syndrome characterized mainly by nail, hair and blood abnormalities.
- Oro acral syndrome: A very rare syndrome characterized mainly by mouth and limb abnormalities.
- Palmoplantar keratoderma punctate, hereditary: An inherited disorder characterized by numerous tiny bumps of thickened skin on the palms and soles. The skin develops numerous hyperkeratototic papules which are usually 1-2 mm in size.
- Paronychia: is often tender bacterial or fungal infection where the nail and skin meet at the side or the base of the finger or toenail
- Patel-Bixler syndrome: A rare disorder characterized by the association of abnormal thickening of skin on palms and soles, nail abnormalities and alopecia.
- Pectus excavatum macrocephaly dysplastic nails: A rare syndrome characterized mainly by a sunken chest, large head and abnormal nails.
- Peripheral vascular disease: Disease of arteries supplying the legs or sometimes arms
- Phenytoin -- Teratogenic Agent: There is evidence to indicate that exposure to Phenytoin during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the level of exposure and the stage of pregnancy that the exposure occurred at.
- Proud-Levine-Carpenter syndrome: A very rare syndrome characterized mainly by abnormal brain development, a small head and genital abnormalities.
- Psoriasis: Psoriasis is an inflammatory skin condition where the defective immune system causes skin cells to grow rapidly. It affects a significant number of people. Arthritis, which can be severe, is associated with the psoriasis in up to a third of cases. Not all patients who are susceptible to the condition will develop it - roughly 10% of those susceptible will actually develop the condition. There are various environmental factors which can trigger the onset of the disease e.g. strep throat (common trigger), some medication, stress and cold weather. Once the disease develops, it may resolve on its own or with treatment or may become a persistent chronic condition. The severity and duration of symptoms is variable.
- Pulmonary fibrosis: A scarring condition that affects the lungs
- Rabson-Mendenhall syndrome: A very rare genetic disorder involving severe insulin resistance which is where the body fails to be able to use insulin which is needed to control blood sugar levels.
- Raynaud's disease: It is a reversible ischemia of the peripheral arterioles. It is a painful sensation affecting the fingers and toes associated with whitening or redness
- Renal failure: A condition characterized by a failure of the kidney to excrete toxic metabolites from the body
- Sener syndrome: A very rare syndrome characterized mainly by an unusual facial appearance and an unusual condition where there a cystic spaces around blood vessels as they enter the brain.
- Septooptic dysplasia -- digital anomalies: A very rare syndrome characterized mainly by finger and toe abnormalities as well as abnormal development of the optic nerve and pituitary gland. Antenatal exposure to sedatives may be a factor in the cause of the disorder.
- Systemic lupus erythematosus: chronic autoimmune disease that can be fatal, though with recent medical advances, fatalities are becoming increasingly rare.
- Tetracycline -- Teratogenic Agent: There is evidence to indicate that exposure to Tetracycline during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the level of exposure and the stage of pregnancy that the exposure occurred at.
- Tetramelic deficiencies -- Ectodermal dysplasia -- deformed ears -- other abnormalities: An extremely rare syndrome characterized by tooth, hair and limb abnormalities. The abnormalities can be quite severe in some cases. The parents may have been related in the reported cases.
- Thymic-Renal-Anal-Lung dysplasia: A rare syndrome characterized by abnormalities involving the lungs, anus, kidneys and thymus.
- Thyrotoxicosis: hypermetabolic clinical syndrome resulting from serum elevations in thyroid hormone levels, specifically free thyroxine (T4), triiodothyronine (T3), or both.
- Tinea: A condition which is characterized by an infection caused by a fungus
- Toe symptoms: Symptoms affecting the toes
- Toenail symptoms: Symptoms of the nails on the toes
- Tricho odonto onycho dermal syndrome: A very rare syndrome characterized by hair, tooth, nail and skin abnormalities.
- Tricho-odonto-onychial dysplasia: A very rare syndrome characterized by abnormal skull calcification, reduced scalp hair and nail and tooth enamel abnormalities.
- Trigonocephaly -- broad thumbs: A rare syndrome characterized mainly by broad thumbs and a prominent triangular shaped forehead.
- Trisomy 22 mosaicism: A very rare chromosomal disorder where there is an extra copy of chromosome 22 in some of the body's cells. Some cases with this chromosomal abnormality have no clinical symptoms. The presence of abnormalities in some cases is dependent on which body cells contain the chromosomal defect.
- Trueb-Burg-Bottani syndrome: A very rare genetic syndrome characterized by hair, teeth and nail abnormalities as well as webbed fingers.
- Tuffli-Laxova syndrome: A rare disorder characterized tooth, nail and skin abnormalities as well as an adrenal cyst.
- Vitamin deficiency: When there is any deficiency of vitamins in the body
- Warts: Wart growths on the skin or genital area.
- Wilson's Disease: Wilson disease, or hepatolenticular degeneration, is a neurodegenerative disease of copper metabolism.
- Wilson's disease: Wilson disease, or hepatolenticular degeneration, is a neurodegenerative disease of copper metabolism.
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