Transposition of great arteries: A congenital malformation where the aorta and pulmonary artery are transposed which causes oxygenated blood from the lungs to be sent back to the lungs and de-oxygenated blood to be sent to body tissues. Often there is some other defect such as an opening in the heart chambers which allows mixing of the blood and hence survival is possible for a short while at least. More detailed information about the symptoms, causes, and treatments of Transposition of great arteries is available below.
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A congenital cardiovascular malformation in which the aorta arises entirely from the right ventricle and the pulmonary artery from the left ventricle, so that the venous return from the peripheral circulation is recirculated by the right ventricle via the aorta to the systemic circulation without being oxygenated in the lungs. - (Source - Diseases Database)
Transposition of great arteries is listed as a "rare disease" by the Office of
Rare Diseases (ORD) of the National Institutes of Health
(NIH). This means that Transposition of great arteries, or a subtype of Transposition of great arteries,
affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)
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