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Trisomy 18 Syndrome

Trisomy 18 Syndrome: Introduction

Trisomy 18 Syndrome: A rare genetic chromosomal syndrome where the child has an extra third copy of chromosome 18. Most fetuses are aborted before term, but a live birth with this condition occurs with a frequency around 1-in-3000. Edwards syndrome is more severe than the more common Down syndrome. Edwards syndrome causes mental retardation and numerous physical defects that often cause an early infant death. The condition has variable severity depending on how many of the body's cells have the extra chromosome and how much of the extra chromosome is duplicated. In severe forms all cells have an extra copy of the complete chromosome 18 whereas milder forms may have only some cells having the extra chromosome. Other mild forms may have an extra copy of only part of chromosome 18 in some or all of the body cells. More detailed information about the symptoms, causes, and treatments of Trisomy 18 Syndrome is available below.

Symptoms of Trisomy 18 Syndrome

Treatments for Trisomy 18 Syndrome

  • Treatment varies depending on the symptoms which can vary quite considerably from case to case
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Home Diagnostic Testing

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Wrongly Diagnosed with Trisomy 18 Syndrome?

Trisomy 18 Syndrome: Related Patient Stories

Trisomy 18 Syndrome: Complications

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Causes of Trisomy 18 Syndrome

  • A genetic defect where there are three copies of part or all of chromosome 18 instead of the normal two. Cases appear to be sporadic with no direct link to inheritance
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Hospitals & Clinics: Trisomy 18 Syndrome

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Prognosis for Trisomy 18 Syndrome

Prognosis for Trisomy 18 Syndrome: The prognosis varies depending on the nature and severity of symptoms present in individual cases. Roughly half of the patients die during early infancy. Survival into the teens does occur but patients often have severe health problems.

Trisomy 18 Syndrome: Broader Related Topics

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More information about Trisomy 18 Syndrome

  1. Trisomy 18 Syndrome: Introduction
  2. Symptoms
  3. Causes
  4. Treatments
  5. Home Testing
  6. Complications
  7. Prognosis
 

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