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Treatments for Type I Hypersensitivity

Treatment List for Type I Hypersensitivity

The list of treatments mentioned in various sources for Type I Hypersensitivity includes the following list. Always seek professional medical advice about any treatment or change in treatment plans.

  • There is no cure. Treatment is aimed at managing symptoms: avoiding allergen, antihistamines, mast cell stabilizers, steroids, cyclosporine and immunotherapy
  • Treatment of Type 1 hypersensitivity is dependant upon the type and severity of allergic symptoms. Treatments for Type 1 hypersensitivity include:
    • Allergen avoidance and minimisation of exposure - including dietary management in food allergies, minimisation of dust mites with strategies in the home environment.
    • Antihistamines - Useful for allergic rhinitis and some allergy mediated skin conditions. Not helpful in asthma except for mild seasonal asthma where allergy may be a precipitant.
    • Nasal sprays - including topical steroids and antiinflammatories used for allergic rhinitis
    • Eyedrops - ketorolac, levocabastine, ketotifen, olopatadine, for allergic conjunctivitis
    • Asthma medications such as inhaled beta agonists and inhaled corticosteroids - used to treat asthma which may have allergy as a contributing factor.
    • Oral steroids - used in short courses for moderate allergic reactions especially with asthma symptoms or skin conditions
    • Desensitisation - evidence is mixed, and efficacy dependant or the type of allergy and specific type of reaction
    • EpiPen - adrenaline delivery device used as first line treatment prior to hospital care for those who have proven anaphylaxis as a result of specific allergies
    • Anaphylaxis is a severe life threatening allergic response. Treatment includes:
      • Hospitalisation
      • IM adrenaline
      • High flow oxygen
      • Intravenous fluids
      • Intravenous and oral steroids
      • Nebulised bronchodilators
      • Nebulised adrenaline for upper airways obstruction

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