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Cyclosporine: A natural cyclic polypeptide immunosuppressant isolated from the fungus Beauveria nivea. The exact mechanism of action of cyclosporine is not known but may involve binding to the cellular protein cytophilin, resulting in inhibition of the enzyme calcineurin. This agent appears to specifically and reversibly inhibit immunocompetent lymphocytes in the G0-or G1-phase of the cell cycle. T-lymphocytes are preferentially inhibited with T-helper cells as the primary target. Cyclosporine also inhibits lymphokine production and release. (NCI04)
Source: Diseases Database
Cyclosporine : 11-residue cyclic peptide produced by certain fungi which has antifungal and T cell specific immunosuppressive properties.
Count: Cyclosporine is listed as a: treatment for 25 conditions; alternative treatment for 0 conditions; preventive treatment for 0 conditions; research treatment for 3 conditions.
Treatments: list of all treatments
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