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Insulin lysine-proline or "lispro" is a synthesized human insulin analog, where "analog" means it is not exactly identical to human insulin. An analog is a protein that is similar to human insulin, but has some advantages over ordinary insulin.
Insulin lispro has the advantage over regular insulin of being very rapid acting. Using insulin lispro allows the diabetic to take the dose just before eating, literally at the first mouth-full, instead of injecting the customary 30 minutes before a meal for traditional Regular (R) insulin. Except for this rapid action, insulin lispro functions just like ordinary insulin, helping both sugar processing and tissue growth and healing.
The rapid action makes insulin lispro very convenient for pre-meal bolus doses, and can help some people get better control for this reason. It is easier to make a dose decision when you can see the food on your plate than dosing based on what you plan to eat in 30 minutes. Insulin lispro's rapid action also makes it better for counteracting the effects of any simple sugars eaten, although it's still not so effective against sugars, and eating sugars is still a bad dietary choice for diabetics. Immediate dosing also removes the risk of taking a shot and then getting interrupted before eating the meal, leading to a low.
Insulin lispro thus has a more rapid and faster potency phase for its processing. It works faster, but it also loses potency faster. This means insulin lispro can be worse than regular insulin for meals that take a long time to digest, such as high-carbo, or carbohydrates mixed with proteins and fats that further delay sugar release. Hence, while most people can get better control with a rapid acting insulin analog, there are also some who have problems because the insulin is "gone" too quickly, leading to later highs, if dosed incorrectly.
Insulin analogs have been available for some time and are available for numerous injection devices. Insulin lispro can also be used in an insulin pump.
Count: Human Insulin Analog (Lispro) is listed as a: treatment for 0 conditions; alternative treatment for 0 conditions; preventive treatment for 0 conditions; research treatment for 0 conditions.
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