Spironolactone

Descriptions of Spironolactone

Spironolactone: A synthetic 17-spironolactone corticosteroid with potassium-sparing diuretic, antihypertensive, and antiandrogen activities. Spironolactone competitively inhibits adrenocortical hormone aldosterone activity in the distal renal tubules, myocardium, and vasculature. This agent may inhibit the pathophysiologic effects of aldosterone produced in excess by various types of malignant and benign tumors. (NCI04)
Source: Diseases Database

Spironolactone : potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules; used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis; its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects.
Source: CRISP

Basic Information: Spironolactone

Count: Spironolactone is listed as a: treatment for 2 conditions; alternative treatment for 0 conditions; preventive treatment for 0 conditions; research treatment for 0 conditions.

Treatments: list of all treatments

List of Diseases with Spironolactone as a Treatment

The following list of conditions have 'Spironolactone' or similar listed as a treatment in our database:

H

• Hirsutism ... spironolactone
• Hypertension ... spironolactone

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