The information below shows a list of types of Under-diagnosed conditions, with information as to the prevalence of each of these types. Estimates of the people affected are calculated based on the available statistic.
| Disease | Prevalence Estimate | US people estimate | Statistic Used for Calculation |
| Silent conditions | N/A | N/A | No information |
| Diabetes | approx 1 in 17 or 5.88% or 16 million people in USA | 15,999,999 | 16 million Americans with 10.3 million diagnosed and 8.1 million women (NWHIC); 65 per 1000 - NHIS95; 8 million - perhaps 16 million if include not-yet-diagnosed. |
| Type 2 Diabetes | approx 1 in 17 or 5.88% or 16 million people in USA | 15,999,999 | 16 million Americans (NWHIC, includes undiagnosed); 7.2 million (actually diagnosed) |
| Whooping cough | N/A | N/A | No information |
| Hypertension | approx 1 in 5 or 18.38% or 50 million people in USA | 49,999,999 | 50 million Americans (NHLBI); 217 per 1000 (NHIS95) |
| Celiac disease | approx 1 in 249 or 0.40% or 1.1 million people in USA | 1,088,000 | 1 in 250 Americans estimated rate; actual diagnosis rate is 1 in 4,700 Americans; 1 in 250 in Italy; 1 in 300 in Ireland; 20,000 diagnosed (Reader's Digest Feb 2004) |
| Colorectal cancer | N/A | N/A | No information |
| Rectal cancer | N/A | N/A | No information |
| Bipolar disorder | approx 1 in 83 or 1.20% or 3.3 million people in USA | 3,264,000 | 1.2 percent of the population; 2.3 million adult Americans (NIMH) |
| High cholesterol | approx 1 in 3 or 37.13% or 101 million people in USA | 101,000,004 | estimated 101 million Americans have cholesterol >= 200 mg/dL (CDC) |
| Arteriosclerosis | approx 1 in 58 or 1.70% or 4.6 million people in USA | 4,624,000 | 17 per 1000 - NHIS95 |
| Osteoporosis | approx 1 in 9 or 10.29% or 28 million people in USA | 28,000,000 | 28 million Americans (10 million with osteoporosis; 18 million with low bone mass); eight million American women and 2 million men (NWHIC) |
| Hemochromatosis | approx 1 in 272 or 0.37% or 1 million people in USA | 999,999 | more than 1 million Americans (CDC); 5 per 1000 in Caucasians (NIDDK); 1-in-200 to 1-in-300 |
| Sexually transmitted diseases | approx 1 in 4 or 23.90% or 65 million people in USA | 64,999,999 | 65 million people living with an incurable STD (CDC) |
| chlamydia | N/A | N/A | No information |
| HPV | approx 1 in 13 or 7.35% or 20 million people in USA | 19,999,999 | 20 million Americans currently infected (NIAID; CDC 2001) |
| trichomoniasis | N/A | N/A | No information |
| bacterial vaginosis | approx 1 in 424 or 0.24% or 640,000 people in USA | 640,000 | 16% of pregnant women (DSTD) |
| gonorrhea | N/A | N/A | No information |
| genital herpes | approx 1 in 4 or 24.63% or 67 million people in USA | 66,999,999 | 67 million people (NIAID) |
| HIV | approx 1 in 302 or 0.33% or 900,000 people in USA | 899,999 | 900,000 Americans (NIAID, quarter are unaware) |
| Kidney disease | approx 1 in 36 or 2.72% or 7.4 million people in USA | 7,399,999 | 7.4 million adults in the USA 1988-94 (American Journal of Kidney Disease) |
| Thyroid disorders | approx 1 in 13 or 7.35% or 20 million people in USA | 19,999,999 | 20 million Americans (NWHIC) |
| Hypothyroidism | N/A | N/A | No information |
| Hashimoto's thyroiditis | approx 1 in 182 or 0.55% or 1.5 million people in USA | 1,490,371 | 1,490,371 adults and 205,159 children in the USA 1996 1 |
| Glaucoma | approx 1 in 136 or 0.74% or 2 million people in USA | 1,999,999 | 2,000,000 people are visually impaired by glaucoma in the US (Research to Prevent Blindness, NISE, NSF) |
| Depression | approx 1 in 18 or 5.30% or 14.4 million people in USA | 14,416,000 | estimated 5.3% adults (USSG); 17 million people; approximately 4% of adolescents get seriously depressed (NIMH); annually 12% of women ; 7% of men; lifetime risk of an episode for women 20%. 3-4 million men USA. |
| Infectious diarrhea | N/A | N/A | No information |
| Fecal incontinence | approx 1 in 41 or 2.39% or 6.5 million people in USA | 6,500,000 | 6.5 million Americans |
| Lactose intolerance | approx 1 in 9 or 11.03% or 30 million people in USA | 29,999,998 | 30 million people to 50 million people (NIDDK 1994); about 25% of population (1994/NIDDK) |
| Polycystic ovary syndrome (PCOS) | approx 1 in 40 or 2.50% or 6.8 million people in USA | 6,800,000 | 5-10% women of childbearing age (20-40); 30% of women have some PCOS symptoms (NWHIC). |
| Flat feet | N/A | N/A | No information |
| Attention deficit hyperactivity disorder | approx 1 in 82 or 1.21% or 3.3 million people in USA | 3,299,999 | 3.3 million children have ADD in USA (NHIS-97); estimated 2 million American children; 3 to 5 percent of all children (NIMH). |
| Sleep disorders | approx 1 in 6 or 14.71% or 40 million people in USA | 39,999,999 | approximately 40 million Americans (NHLBI) |
| sleep apnea | approx 1 in 15 or 6.62% or 18 million people in USA | 18,000,000 | estimated 18 million Americans (NHLBI) |
| obstructive sleep apnea | approx 1 in 22 or 4.41% or 12 million people in USA | 11,999,999 | 12 million Americans |
| insomnia | approx 1 in 8 or 11.76% or 32 million people in USA | 31,999,999 | 32 million (unreliable estimate) |
| narcolepsy | approx 1 in 1,359 or 0.07% or 200,000 people in USA | 200,000 | 200,000 Americans (NHLBI estimate); 50,000 diagnosed. |
| Asthma | approx 1 in 15 or 6.40% or 17.4 million people in USA | 17,408,000 | 6.4% USA (NIAID); 17 million Americans (NIAID) including 5 million children; 8.1 million children (NHIS-97), 51 per 1000 - NHIS95; 14.5 million; 5% of population (NWHIC); 14.9 million in 1995 (NHLBI) |
| Von Willebrand disease | approx 1 in 90 or 1.10% or 3 million people in USA | 2,999,999 | estimated 3 million mostly undiagnosed |
For more information about types of Under-diagnosed conditions, refer to our section on types of Under-diagnosed conditions.
The medical term 'prevalence' of Under-diagnosed conditions usually refers to the estimated population of people who are managing Under-diagnosed conditions at any given time, whereas the annual diagnosis rate of new cases of Under-diagnosed conditions is called the 'incidence'. For more information on prevalence and incidence statistics, see about prevalence and incidence statistics.
Footnotes:
Tools & Services:
Medical Articles:
1. Rose and Mackay, 1998, The Autoimmune Diseases, Third Edition
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