Wegener's granulomatosis: Wegener's granulomatosis is an uncommon disease, characterized by inflammation of the blood vessels (vasculitis). This inflammation ... more about Wegener's granulomatosis.
Wegener's granulomatosis: A rare disease involving blood vessel inflammation which can affect the blood flow to various tissues and organs and hence cause damage. The respiratory system and the kidneys are the main systems affected. More detailed information about the symptoms, causes, and treatments of Wegener's granulomatosis is available below.
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Prognosis for Wegener's granulomatosis: progressive fatal condition, mortality 28% at 5 years
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Wegener's granulomatosis is an uncommon disease, characterized by inflammation of the blood vessels (vasculitis). This inflammation results in a reduction of oxygen in the blood and damages vital organs of the body by restricting blood flow to those organs and destroying normal tissue. Although vasculitis can damage any organ system, Wegener's granulomatosis primarily affects the respiratory tract (sinuses, nose, trachea [windpipe] and lungs) and the kidneys. This disorder can occur at any age and strikes men and women equally. It is rare in African Americans compared to whites. The cause of Wegener's granulomatosis is not known. (Source: excerpt from Wegener's Granulomatosis, NIAID Fact Sheet: NIAID)
Multisystem disease chiefly affecting males, characterized by necrotizing granulomatous vasculitis involving the upper and lower respiratory tracts, glomerulonephritis, and variable degrees of systemic small vessel vasculitis; considered an aberrant hypersensitivity reaction to an unknown antigen. - (Source - Diseases Database)
Wegener's granulomatosis is listed as a "rare disease" by the Office of
Rare Diseases (ORD) of the National Institutes of Health
(NIH). This means that Wegener's granulomatosis, or a subtype of Wegener's granulomatosis,
affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)
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