Symptoms of Wilson's Disease
Symptoms of Wilson's Disease: Introduction
People with Wilson's disease have the disorder from birth, but generally do not begin to experience symptoms until they are at least four years of age. Symptoms may not occur until the late teens.
Wilson's disease results in the build-up of high levels of copper in the liver. This damages and scars liver tissue, resulting in symptoms, such as abdominal pain, abdominal distention, vomiting blood, enlarged spleen, and jaundice. Left untreated, excessive copper spills out of the liver into the bloodstream and is carried to other organs in the body, such as the kidneys, nervous system, and eyes. Excessive copper damages these organs as well resulting in symptoms, such as loss of muscle control, abnormal muscle movements, tremors, poor cognitive functioning, memory loss, behavioral changes, impaired speech, and weakness.
If Wilson's disease is not diagnosed and treated promptly, it can lead to serious permanent, even life-threatening complications, such as cirrhosis of the liver, liver necrosis, severe brain damage, dementia, kidney damage, liver failure, and death....more about Wilson's Disease »
Symptoms of Wilson's Disease
The list of signs and symptoms mentioned in various sources
for Wilson's Disease includes the 84
symptoms listed below:
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Wilson's Disease: Symptom Checkers
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Wilson's Disease: Symptom Assessment Questionnaires
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Wilson's Disease: Complications
Review medical complications possibly associated with Wilson's Disease:
Diagnostic testing of medical conditions related to Wilson's Disease:
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Do I have Wilson's Disease?
Wilson's Disease: Medical Mistakes
Wilson's Disease: Undiagnosed Conditions
Diseases that may be commonly undiagnosed in related medical areas:
Home Diagnostic Testing
Home medical tests related to Wilson's Disease:
- Child Behavior: Home Testing
- Mental Health (Adults): Home Testing
- Bladder & Urinary Health: Home Testing:
- Liver Health & Hepatitis: Home Testing
- Mental Health: Home Testing:
- Kidney Health: Home Testing:
- Nerve Neuropathy: Related Home Testing:
- Brain & Neurological Disorders: Related Home Testing:
- more home tests...»
Wrongly Diagnosed with Wilson's Disease?
The list of other diseases or medical conditions
that may be on the differential diagnosis list of alternative diagnoses
for Wilson's Disease includes:
See the full list of 14
Wilson's Disease: Research Doctors & Specialists
- Nerve Specialists:
- Mental Health Specialists:
- Neurology (Brain/CNS Specialists):
- more specialists...»
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More about symptoms of Wilson's Disease:
More information about symptoms of Wilson's Disease and related conditions:
Other Possible Causes of these Symptoms
Click on any of the symptoms below to see a full list
of other causes including diseases, medical conditions, toxins, drug interactions,
or drug side effect causes of that symptom.
Article Excerpts About Symptoms of Wilson's Disease:
Genes and Disease by the National Center for Biotechnology (Excerpt)
Liver disease is the most common symptom in children; neurological disease is most common in young adults. The cornea of the eye can also be affected: the 'Kayser-Fleischer ring' is a deep copper-colored ring at the periphery of the cornea, and is thought to represent copper deposits.
(Source: Genes and Disease by the National Center for Biotechnology)
Wilson's Disease: NIDDK (Excerpt)
characteristic sign is the Kayser-Fleischer ring--a rusty brown ring
around the cornea of the eye that can be seen only through an eye exam.
Other signs depend on whether the damage occurs in the liver, blood,
central nervous system, urinary system, or musculoskeletal system. Many
signs would be detected only by a doctor, like swelling of the liver and
spleen; fluid buildup in the lining of the abdomen; anemia; low platelet
and white blood cell count in the blood; high levels of amino acids,
protein, uric acid, and carbohydrates in urine; and softening of the
bones. Some symptoms are more obvious, like jaundice, which appears as
yellowing of the eyes and skin; vomiting blood; speech and language
problems; tremors in the arms and hands; and rigid muscles.
(Source: excerpt from Wilson's Disease: NIDDK)
NINDS Wilson's Disease Information Page: NINDS (Excerpt)
The primary consequence for
approximately 40 percent of patients with Wilson's is liver disease. In
other patients the first symptoms are either neurological or psychiatric
or both, and include tremor, rigidity, drooling, difficulty with speech,
abrupt personality change, grossly inappropriate behavior and unexplicable
deterioration of school work, neurosis or psychosis.
(Source: excerpt from NINDS Wilson's Disease Information Page: NINDS)
Wilson's Disease as a Cause of Symptoms or Medical Conditions
When considering symptoms of Wilson's Disease, it is also important to consider Wilson's Disease as a possible cause of other medical conditions.
The Disease Database lists the following medical conditions that Wilson's Disease may cause:
- (Source - Diseases Database)
Wilson's Disease as a symptom:
For a more detailed analysis of Wilson's Disease as a symptom, including causes, drug side effect causes, and drug interaction causes, please see our Symptom Center information for Wilson's Disease.
Wilson's Disease: Onset and Incubation
Onset of Wilson's Disease: The onset of liver disease is usually at the age of 8-16 years.
Medical articles and books on symptoms:
These general reference articles may be of interest
in relation to medical signs and symptoms of disease in general:
Full list of premium articles on symptoms and diagnosis
About signs and symptoms of Wilson's Disease:
The symptom information on this page
attempts to provide a list of some possible signs and symptoms of Wilson's Disease.
This signs and symptoms information for Wilson's Disease has been gathered from various sources,
may not be fully accurate,
and may not be the full list of Wilson's Disease signs or Wilson's Disease symptoms.
Furthermore, signs and symptoms of Wilson's Disease may vary on an individual basis for each patient.
Only your doctor can provide adequate diagnosis of any signs or symptoms and whether they
are indeed Wilson's Disease symptoms.