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Treatments for Wilson's Disease

Treatments for Wilson's Disease:

Wilson's disease is not curable and requires treatment throughout the lifespan to prevent the build-up of excessive copper in the body. However, prompt and consistent treatment can ensure that people with Wilson's disease will lead active, normal lives and minimizes the chance of developing serious complications, such as brain damage, kidney damage, and liver failure.

Medications, such as zinc of penicillamine or trientine, are used to treat Wilson's disease. The mineral supplement zinc works by blocking the absorption of copper by the body. Penicillamine and trientine work by helping to remove excessive copper from the body's tissues.

People with Wilson's disease also need to avoid or eliminate foods that are high in copper from their diets. These include nuts, chocolate, dried fruit, liver, shellfish and mushrooms. Consultation with a registered dietician can be very helpful in helping a person with Wilson's disease to choose and stick to a diet that is low in copper.

Treatment List for Wilson's Disease

The list of treatments mentioned in various sources for Wilson's Disease includes the following list. Always seek professional medical advice about any treatment or change in treatment plans.

Wilson's Disease: Is the Diagnosis Correct?

The first step in getting correct treatment is to get a correct diagnosis. Differential diagnosis list for Wilson's Disease may include:

Hidden causes of Wilson's Disease may be incorrectly diagnosed:

  • Wilson disease is an autosomal recessive inherited condition caused by mutations or deletions of the ATP7B protein encoded by chromosome subbands 13q14.3-q 21.1
  • more causes...»

Wilson's Disease: Marketplace Products, Discounts & Offers

Products, offers and promotion categories available for Wilson's Disease:

Wilson's Disease: Research Doctors & Specialists

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Drugs and Medications used to treat Wilson's Disease:

Note:You must always seek professional medical advice about any prescription drug, OTC drug, medication, treatment or change in treatment plans.

Some of the different medications used in the treatment of Wilson's Disease include:

Hospitals & Medical Clinics: Wilson's Disease

Research quality ratings and patient incidents/safety measures for hospitals and medical facilities in specialties related to Wilson's Disease:

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Choosing the Best Treatment Hospital: More general information, not necessarily in relation to Wilson's Disease, on hospital and medical facility performance and surgical care quality:

Medical news summaries about treatments for Wilson's Disease:

The following medical news items are relevant to treatment of Wilson's Disease:

Discussion of treatments for Wilson's Disease:

Wilson's Disease: NIDDK (Excerpt)

The disease is treated with lifelong use of D-penicillamine or trientine hydrochloride, drugs that help remove copper from tissue. Patients will also need to take vitamin B6 and follow a low-copper diet, which means avoiding mushrooms, nuts, chocolate, dried fruit, liver, and shellfish. Taking extra zinc may be helpful in blocking the intestines' absorption of copper. (Source: excerpt from Wilson's Disease: NIDDK)

NINDS Wilson's Disease Information Page: NINDS (Excerpt)

Treatment of Wilson's disease generally consists of anti-copper agents to remove excess copper from the body and to prevent it from reaccumulating. Most cases are treated with the drugs zinc acetate, trientine, or penicillamine. Penicillamine and trientine increase urinary excretion of copper, however, both drugs can cause serious side effects. Zinc acetate which blocks the absorption of copper, increases copper excretion in the stool, and causes no serious side affects is often considered the treatment of choice. Tetrathiomolybdate, an experimental drug, also shows promise in treating Wilson's disease. In rare cases in which there is severe liver disease, a liver transplant may be needed. (Source: excerpt from NINDS Wilson's Disease Information Page: NINDS)

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