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Diseases » Acromegaly » Glossary

Glossary for Acromegaly

  • Acromegaloid, Cutis Verticis Gyrata, Corneal Leukoma Syndrome: A rare condition characterized by the association of acromegaly, cutis verticis gyrate and corneal leukoma.
  • Acromegaly due to growth hormone-secreting pituitary adenoma: Pituitary adenomas are benign monoclonal neoplasms of the anterior pituitary gland, accounting for approximately 15% of intracranial tumors.
  • Addison's Disease: A rare progressive hormonal disorder characterized by insufficient production of certain hormones called adrenal corticosteroids.
  • Adenoma: General term for a benign tumor of a gland
  • Adrenal Cancer: A malignant cancer that develops in the adrenal gland. The tumor may be nonfunctioning (does not produce hormones) or functioning in which case excessive levels of hormones can cause a variety of symptoms depending on which hormone is involved. Adrenal hormones made in the cortex (outer part of the gland) are aldosterone, corticosteroids and androgenic steroids. Adrenalin and noradrenalin are the hormones made in the medulla (central part of the adrenal gland).
  • Amyloidosis: A rare group of metabolic disorders where a protein called amyloid accumulates in body organs and tissues where it can cause damage and is potentially fatal. Symptoms depend on the organs involved. There are numerous forms of the condition: primary amyloidosis, secondary amyloidosis, hemodialysis-associated amyloidosis and familial amyloidosis.
  • Arthritis: General name for any type of joint inflammation, but often means age-related osteoarthritis.
  • Bizarre medical conditions: Various unusual and unexpected medical disorders
  • Blurred vision: Blurriness of vision or images.
  • Cardiomyopathy: Any disease of the heart muscle
  • Cardiovascular Disease: Diseases of the heart or blood vessels including cerebrovascular diseases such as stroke.
  • Carney syndrome: A very rare syndrome characterized by spotty pigmentation on the skin and the development of multiple benign tumors (myxoma) that can occur just about anywhere in the body but mainly in the skin, breast and heart and endocrine glands such as the thyroid and pituitary gland. The symptoms are highly variable depending on the location, size and number of tumors. Endocrine gland tumors can affect hormone production and hence result in a range of symptoms.
  • Carpal Tunnel Syndrome: Hand or wrist problems; often from repetitive motion.
  • Colorectal Polyps: Polyp growths in the colon or rectum.
  • Cushing's syndrome: A rare syndrome where excessive secretion of corticosteroids by the adrenal cortex leads to a variety of symptoms. Hormone-secreting adrenal or pituitary tumors are often the cause of the excessive corticosteroid secretion.
  • Cutis verticis gyrata: A rare condition characterized by skin folds and furrows on the scalp and face. It is often associated with various other conditions and abnormalities.
  • Diabetes: Failing or reduced ability of the body to handle sugars.
  • Ectopic acromegaly: Ectopic acromegaly is a rare syndrome (less than 1% of acromegalic patients) caused by ectopic growth hormone-releasing hormone (GHRH) or growth hormone (GH)-producing tumors.
  • Edema: Fluid retention in tissues
  • Endocrine system conditions: Medical conditions affecting the endocrine systems, such as the related hormones or glands.
  • Enlarged hands: abnormal fluid collection in the interstial tissue
  • Failure To Thrive: Slow growth or inadequate weight gain of an infant or child.
  • Foot swelling: Oedema of the foot.
  • Geographic Tongue: A form of tongue inflammation where smooth, migrating patches form on the tongue.
  • Gigantism: A rare endocrine disorder where excess growth hormone is produced prior to puberty.
  • Growth-hormone secreting pituitary adenoma, colonic polyposis, lipomatosis, lentigines and renal carcinoma: An inherited cancer syndrome involving kidney cancer, polyposis of the colon and a pituitary tumor.
  • Hand swelling: Swelling of one or both hands
  • Headache: In medicine a headache or cephalalgia is a symptom of a number of different conditions of the head and sometimes neck. Some of the causes are benign while others are medical emergencies. It ranks among the most common pain complaints
  • Hirsutism: Increased hairiness
  • Hyperlipidaemia: An elevated amount of lipids in the blood of the body
  • Hyperphosphataemia: An increased level of phosphate in the circulation above that which is considered normal
  • Hypertension: High blood pressure
  • Impaired glucose tolerance: Mild glucose metabolism problems not severe enough to be called diabetes.
  • Impotence: Inability to attain or sustain an erection.
  • Insulin resistance, short fifth metacarpals: A rare syndrome characterized by short fifth fingers and fifth hand bones as well as insulin resistance.
  • Large feet: Large size of the feet
  • Lung cancer: Lung cancer is a disease of uncontrolled cell growth in tissues of the lung. This growth may lead to metastasis, which is the invasion of adjacent tissue and infiltration beyond the lungs. Most lung tumors are malignant.
  • Macroglossia: Abnormally large tongue.
  • McCune-Albright Syndrome: A rare genetic multisystem disorder characterized by abnormal skin pigmentation and endocrine gland dysfunction and replacement of parts of bone tissue with fibrous material.
  • Menstrual conditions: Any condition that is associated with the female menstrual cycle
  • Mental retardation, X-linked -- acromegaly -- hyperactivity: A rare syndrome characterized mainly by mental retardation, hyperactivity and enlarged hands, feet and testes.
  • Musculoskeletal conditions: Medical conditions affecting the musculoskeletal system of bones, muscles and related structures.
  • Myxedema: Skin and tissue disorder usually due to hypothyroidism
  • Nevi -- atrial myxoma -- myxoid neurofibromata -- ephelides: A very rare syndrome characterized by spotty pigmentation on the skin and the development of multiple benign tumors (myxoma) that can occur just about anywhere in the body but mainly in the skin, breast and heart and endocrine glands such as the thyroid and pituitary gland. The symptoms are highly variable depending on the location, size and number of tumors. Endocrine gland tumors can affect hormone production and hence result in a range of symptoms.
  • Obesity: An increase in the body weight greater than that required for normal function that is characterised by the accumulation of excessive fat
  • Optic nerve disorder: Any condition which impairs the function of the optic nerve. Examples of such conditions includes glaucoma, optic nerve inflammation and impaired blood supply to the optic nerve.
  • Pachydermoperiostosis: A rare genetic ectodermal disorder characterized by thick coarse skin and limb clubbing.
  • Pancreatic cancer: Pancreatic cancer is a malignant neoplasm of the pancreas
  • Panhypopituitarism: A rare condition where all pituitary hormones are absent or reduced. The condition may be congenital or acquired through such things as pituitary tumors. The pituitary gland regulates the activity of other endocrine glands as well as controlling growth. Other endocrine glands include adrenal, parathyroid, thyroid, pancreas, ovaries and testes. Symptoms can vary greatly depending on the degree of deficiency of the various hormones.
  • Parotid gland enlargement: Parotid gland enlargement refers to swelling or puffiness of the parotid gland.
  • Peripheral neuropathy: Peripheral neuropathy is the term for damage to nerves of the peripheral nervous system, which may be caused either by diseases of the nerve or from the side-effects of systemic illness.
  • Pituitary Cancer: Cancer of the pituitary gland.
  • Pituitary conditions: Any condition that affects the pituitary
  • Polycystic ovary syndrome: Polycystic ovary syndrome (PCOS) is an endocrine disorder that affects approximately 5% of all women.
  • Prolactinoma: Benign cancer of the pituitary gland producing prolactin.
  • Proximal muscle weakness: Weakness of the proximal muscles
  • Raynaud's phenomenon: Blood vessel constriction attacks affecting fingers and/or toes.
  • Sialadenitis: Salivary gland inflammation due to obstruction of the salivary gland or a duct.
  • Swollen bone: Enlarged, swollen, or misshapen bones
  • Type 2 diabetes: Most common diabetes in adults, usually progressing slowly, mostly treated without insulin at diagnosis.
  • Vague symptoms: Vague, unclear, mild or non-specific symptoms
  • Weight Gain: An increase in weight for any reason.


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