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Causes of Addison's Disease

List of causes of Addison's Disease

Following is a list of causes or underlying conditions (see also Misdiagnosis of underlying causes of Addison's Disease) that could possibly cause Addison's Disease includes:

  • Tuberculosis
  • Polyendocrine deficiency syndrome
  • Chronic infections - mainly fungal infections
  • Adrenal cancer
  • Amyloidosis
  • Adrenal gland removal
  • Adrenal gland physical damage
  • The underlying cause of Addison's might be the pituitary gland rather than the adrenal glands:
    • Pituitary tumor
    • Pituitary infection
    • Pituitary tumor radiation treatment
    • Hypothalamus surgery or removal
    • Pituitary gland tumor removal - the removal of ACTH-producing tumors of the pituitary gland (Cushing's disease) can lead to a temporary form of Addison's disease, requiring treatment.

Addison's Disease Causes: Risk Factors

The following conditions have been cited in various sources as potentially causal risk factors related to Addison's Disease:

Addison's Disease Causes: Male-Female Gender Ratio

Gender of Patients for Addison's Disease: Mostly women; but occurs in both sexes...more »

Addison's Disease: Related Medical Conditions

To research the causes of Addison's Disease, consider researching the causes of these these diseases that may be similar, or associated with Addison's Disease:

Addison's Disease: Causes and Types

Causes of Types of Addison's Disease: Review the cause informationfor the various types of Addison's Disease:

  • Primary Adrenal Insufficiency - 70%, autoimmune destruction of the adrenal cortex
  • Secondary Adrenal Insufficiency - caused by a tumor or another underlying cause.
  • Tuberculosis-caused Addison's
  • more types...»

Causes of Broader Categories of Addison's Disease: Review the causal information about the various more general categories of medical conditions:

Addison's Disease as a complication of other conditions:

Other conditions that might have Addison's Disease as a complication may, potentially, be an underlying cause of Addison's Disease. Our database lists the following as having Addison's Disease as a complication of that condition:

Addison's Disease as a symptom:

Conditions listing Addison's Disease as a symptom may also be potential underlying causes of Addison's Disease. Our database lists the following as having Addison's Disease as a symptom of that condition:

Medications or substances causing Addison's Disease:

The following drugs, medications, substances or toxins are some of the possible causes of Addison's Disease as a symptom. This list is incomplete and various other drugs or substances may cause your symptoms. Always advise your doctor of any medications or treatments you are using, including prescription, over-the-counter, supplements, herbal or alternative treatments.

What causes Addison's Disease?

Causes: Addison's Disease: Failure of adrenal glands to produce cortisol and sometimes aldosterone.
Failure to produce adequate levels of cortisol, or adrenal insufficiency, can occur for different reasons. The problem may be due to a disorder of the adrenal glands themselves (primary adrenal insufficiency) or to inadequate secretion of ACTH by the pituitary gland (secondary adrenal insufficiency). (Source: excerpt from Addison's Disease: NIDDK)

Cause statistics for Addison's Disease:

The following are statistics from various sources about the causes of Addison's Disease:

  • 70% of reported cases of Addison’s disease are caused by autoimmune disorders in the US (NIDDK, NIH, 2002)
  • more statistics...»

Related information on causes of Addison's Disease:

As with all medical conditions, there may be many causal factors. Further relevant information on causes of Addison's Disease may be found in:


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