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Diseases » Alport Syndrome » Complications

Complications of Alport Syndrome

Complications list for Alport Syndrome:

The list of complications that have been mentioned in various sources for Alport Syndrome includes:

Complications and sequelae of Alport Syndrome from the Diseases Database include:

Source: Diseases Database

See also the symptoms of Alport Syndrome and Alport Syndrome: Introduction.

Complications of Alport Syndrome:

Genes and Disease by the National Center for Biotechnology (Excerpt)

The syndrome was named for Dr. Alport who in 1927 described a British family in which many members developed renal disease as well as deafness. He noted that affected men in the family died as a result of their kidney problems, whereas females were less affected and lived until old age. (Source: Genes and Disease by the National Center for Biotechnology)

Genes and Disease by the National Center for Biotechnology (Excerpt)

Type IV collagen is found in basement membranes (BM), which are selective barriers between cells. In the kidney, the glomerular BM filters waste products into the urine while keeping useful molecules within the blood stream. In AS, the abnormal collagen disrupts this filter, leading to the loss of proteins and red blood cells into the urine. Blood in the urine (hematuria) is a sign common to all types of AS. In the ear, abnormal collagen in the cochlea results in a progressive deafness in which the ability to hear high tones is lost first. Abnormal collagen can also affect the lens of the eye. (Source: Genes and Disease by the National Center for Biotechnology)

You may also want to research other symptoms in our Symptoms Center.

About complications:

Complications of Alport Syndrome are secondary conditions, symptoms, or other disorders that are caused by Alport Syndrome. In many cases the distinction between symptoms of Alport Syndrome and complications of Alport Syndrome is unclear or arbitrary.


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