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Treatments for Analgesic nephropathy syndrome

Treatment List for Analgesic nephropathy syndrome

The list of treatments mentioned in various sources for Analgesic nephropathy syndrome includes the following list. Always seek professional medical advice about any treatment or change in treatment plans.

  • Cessation of analgesics contributing to kidney damage. This may allow for normalisation of renal function, or slow the progression of renal disease
  • Observation if renal impairment is mild or improving
  • Avoidance of medications that may contribute to further renal damage - NSAID's, IV contrast
  • Smoking cessation - people who continue to smoke progress to end stage renal failure sooner
  • Close management of high blood pressure, whether it is a cause or result of renal disease
  • Use of ACE inhibitors - in patients both with and without proteinuria, has been shown to slow the progression of renal failure
  • Dietary management dependin upon the severity of renal impairment
    • Protein restriction - may have a role in slowing the progress of renal failure, and is important to manage uremic symptoms in advanced failure, but needs to be managed carefully to avoid malnutrition
    • Salt and water restriction as necessary to manage fluid overload
    • Phosphate restriction
    • Potassium restriction as necessary
  • Management of chronic renal failure as required
    • Erythropoietin agonists - for management of anaemia associated with chronic renal failure
    • Phosphate binders - for management of hyperphosphatemia in chronic renal failure
    • Calcium supplements - for hypocalcaemia associated with chronic renal failure
    • Calcitriol and other Vitamin D supplements - for hypocalcaemia and hyperparathyroidism associated with chronic renal failure
    • Sodium bicarbonate - for acid-base disturbance
    • Renal dialysis - used when there are manifestations of uraemia and the GFR is < 10mL/min
    • Renal transplantation

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