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Glossary for Antiphospholipid syndrome

  • Artery symptoms: Symptoms affecting the arteries (large blood vessels)
  • Autoimmune diseases: A group of disorders in which the primary cause is the an inflammatory reaction caused by the body's own immune system attacking tissues
  • Bleeding and coagulation conditions:
  • Blood clot: A coagulum that is located in the blood stream due to the aggregation of blood factors
  • Blood clots: Multiple coagulums that are located in the blood stream due to the aggregation of blood factors
  • Budd-Chiari syndrome: Budd-Chiari syndrome is the clinical picture caused by occlusion of the hepatic veins. It presents with the classical triad of abdominal pain, ascites and hepatomegaly.
  • Circulatory system conditions: Medical conditions affecting the heart and the circulatory system.
  • Clotting symptoms: Symptoms affecting the blood's ability to clot
  • Death: The cessation of life
  • Heart valve diseases: Diseases that affect the valves of the heart
  • Hemolytic anemia: Hemolytic anemia is a term used to describe the premature desctruction of red blood cells. Red blood cells are normally broken down every 3-4 months and replaced but in haemolytic anemia the red blood cells are broken down at a faster rate than they can be replenished. The causes are numerous and the severity ranges considerably. Severe cases can lead to death.
  • Immune disorders: Disorders that affect the immune system
  • Kidney symptoms: Symptoms affecting one or both kidneys.
  • Leg ulcers: Ulcers or sores on the legs.
  • Lupus: Autoimmune disease with numerous effects on various organs and linings.
  • Migraine: Chronic recurring headaches with or without a preceding aura.
  • Miscarriage: Loss of fetus without human interference
  • Neutropenia: Reduced number of granulocytes in the blood
  • Polyendocrine deficiency syndrome: A condition where more than one endocrine gland fails to function normally in terms of production of hormones. Symptoms can vary depending on the glands involved and the severity of the gland dysfunction.
  • Portal vein thrombosis: Clotting or obstruction of blood flow along the portal vein and into the liver. This causes blood to back up and results various problems such as enlarged spleen and abdominal pain. The obstruction can occur acutely (over a short space of time) or chronically (over a longer period of time). The portal vein collects blood from the intestines and spleen and carries it to the liver.
  • Primary pulmonary hypertension: Primary pulmonary hypertension refers to high blood pressure in the arteries that carry blood to the lungs for no apparent reason. Blood pressure in other parts of the body is normal or sometimes even low.
  • Stillbirth: Where a woman delivers a child who is dead
  • Syphilis: A sexually transmitted disease caused by a bacteria (Treponema pallidum). The condition is often asymptomatic in the early stages but one or more sores may be present in the early stages. Untreated syphilis usually results in remission of visible symptoms but further severe damage may occur to internal organs and other body tissues which can result in death.
  • Thrombocytopenia: Decreased platelets in the blood
  • Thrombophilia:
  • Ulcer: A local defect in the mucosa
  • Vasculitis: Inflammation of a blood or lymph vessel
  • Venous Thrombosis: Formation of a blood clot in a vein. The clot can form in superficial veins and cause few if any symptoms or it can form in the deeper, larger leg veins which can be life-threatening in serious cases. A part of the clot can break off and travel (embolism) to the heart or lungs where it can cause serious problems.


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