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Article title: NHLBI, Heart Failure: NHLBI
Conditions: Heart Failure, Cardiomyoplasty, Congestive heart failure, Diastolic heart failure (type of Heart failure), Echocardiography, Electrocardiogram, Systolic heart failure (type of Heart failure)
The term heart failure suggests a sudden and complete stop of heart activity. But, actually, the heart does not suddenly stop. Rather, heart failure usually develops slowly, often over years, as the heart gradually loses its pumping ability and works less efficiently. Some people may not become aware of their condition until symptoms appear years after their heart began its decline.
How serious the condition is depends on how much pumping capacity the heart has lost. Nearly everyone loses some pumping capacity as he or she ages. But the loss is significantly more in heart failure and often results from a heart attack or other disease that damages the heart.
The severity of the condition determines the impact it has on a person's life. At one end of the spectrum, the mild form of heart failure may have little effect on a person's life; at the other end, severe heart failure can interfere with even simple activities and prove fatal. Between those extremes, treatment often helps people lead full lives.
But all forms of heart failure, even the mildest, are a serious health problem, which must be treated. To improve their chance of living longer, patients must take care of themselves, see their physician regularly, and closely follow treatments.
congestive heart failure is often used to describe all patients with heart failure. In reality, congestion (the buildup of fluid) is just one feature of the condition and does not occur in all patients. There are two main categories of heart failure although within each category, symptoms and effects may differ from patient to patient. The two categories are:
Heart failure causes 39,000 deaths a year and is a contributing factor in another 225,000 deaths. The death rate attributed to heart failure rose by 64 percent from 1970 to 1990, while the death rate from coronary heart disease dropped by 49 percent during the same period. Heart failure mortality is about twice as high for African Americans as whites for all age groups.
In a sense, heart failure's growing presence as a health problem reflects the Nation's changing population: More people are living longer. People age 65 and older represent the fastest growing segment of the population, and the risk of heart failure increases with age. The condition affects 1 percent of people age 50, but about 5 percent of people age 75.
As a symptom of underlying heart disease, heart failure is closely associated with the major risk factors for coronary heart disease: smoking, high cholesterol levels, hypertension (persistent high blood pressure), diabetes and abnormal blood sugar levels, and obesity. A person can change or eliminate those risk factors and thus lower their risk of developing or aggravating their heart disease and heart failure.
Among prominent risk factors, hypertension (high blood pressure) and diabetes are particularly important. Uncontrolled high blood pressure increases the risk of heart failure by 200 percent, compared with those who do not have hypertension. Moreover, the degree of risk appears directly related to the severity of the high blood pressure.
Persons with diabetes have about a two- to eightfold greater risk of heart failure than those without diabetes. Women with diabetes have a greater risk of heart failure than men with diabetes. Part of the risk comes from diabetes' association with other heart failure risk factors, such as high blood pressure, obesity, and high cholesterol levels. However, the disease process in diabetes also damages the heart muscle.
The presence of coronary disease is among the greatest risks for heart failure. Muscle damage and scarring caused by a heart attack greatly increase the risk of heart failure. Cardiac arrhythmias, or irregular heartbeats, also raise heart failure risk. Any disorder that causes abnormal swelling or thickening of the heart sets the stage for heart failure.
In some people, heart failure arises from problems with heart valves, the flap-like structures that help regulate blood flow through the heart. Infections in the heart are another source of increased risk for heart failure.
A single risk factor may be sufficient to cause heart failure, but a combination of factors dramatically increases the risk. Advanced age adds to the potential impact of any heart failure risk.
Finally, genetic abnormalities contribute to the risk for certain types of heart disease, which in turn may lead to heart failure. However, in most instances, a specific genetic link to heart failure has not been identified.
("dyspnea"). In heart failure, this may result from excess fluid in the lungs. The breathing difficulties may occur at rest or during exercise. In some cases, congestion may be severe enough to prevent or interrupt sleep.
Fatigue or easy tiring is another common symptom. As the heart's pumping capacity decreases, muscles and other tissues receive less oxygen and nutrition, which are carried in the blood. Without proper "fuel," the body cannot perform as much work, which translates into fatigue.
Fluid accumulation, or edema, may cause swelling of the feet, ankles, legs, and occasionally, the abdomen. Excess fluid retained by the body may result in weight gain, which sometimes occurs fairly quickly.
Persistent coughing is another common sign, especially coughing that regularly produces mucus or pink, blood-tinged sputum. Some people develop raspy breathing or wheezing.
Because heart failure usually develops slowly, the symptoms may not appear until the condition has progressed over years. The heart hides the underlying problem by making adjustments that delay--but do not prevent--the eventual loss in pumping capacity. The heart adjusts, or compensates, in three ways to cope with and hide the effects of heart failure:
heart failure during a physical examination. Readily identifiable signs are shortness of breath, fatigue, and swollen ankles and feet. The physician also will check for the presence of risk factors, such as hypertension, obesity, and a history of heart problems. Using a stethoscope, the physician can listen to a patient breathe and identify the sounds of lung congestion. The stethoscope also picks up the abnormal heart sounds indicative of heart failure.
If neither the symptoms nor the patient's history point to a clear-cut diagnosis, the physician may recommend any of a variety of laboratory tests, including, initially, an electrocardiogram, which uses recording devices placed on the chest to evaluate the electrical activity of a patient's heartbeat.
Echocardiography is another means of evaluating heart function from outside the body. Sound waves bounced off the heart are recorded and translated into images. The pictures can reveal abnormal heart size, shape, and movement. Echocardiography also can be used to calculate a patient's ejection fraction, a measure of the amount of blood pumped out when the heart contracts.
Another possible test is the chest x ray, which also determines the heart's size and shape, as well as the presence of congestion in the lungs.
Tests help rule out other possible causes of symptoms. The symptoms of heart failure can result when the heart is made to work too hard, instead of from damaged muscle. Conditions that overload the heart occur rarely and include severe anemia and thyrotoxicosis (a disease resulting from an overactive thyroid gland).
However, for the common forms of heart failure--those due to damaged heart muscle--no known cure exists. But treatment for these forms may be quite successful. The treatment seeks to improve patients' quality of life and length of survival through lifestyle change and drug therapy.
Patients can minimize the effects of heart failure by controlling the risk factors for heart disease. Obvious steps include quitting smoking, losing weight if necessary, abstaining from alcohol, and making dietary changes to reduce the amount of salt and fat consumed. Regular, modest exercise is also helpful for many patients, though the amount and intensity should be carefully monitored by a physician.
But, even with lifestyle changes, most heart failure patients must take medication. Many patients receive two or more drugs.
Several types of drugs have proven useful in the treatment of heart failure:
Patients who cannot take ACE inhibitors may get a nitrate and/or a drug called hydralazine, each of which helps relax tension in blood vessels to improve blood flow.
Sometimes, heart failure is life-threatening. Usually, this happens when drug therapy and lifestyle changes fail to control its symptoms. In such cases, a heart transplant may be the only treatment option. However, candidates for transplantation often have to wait months or even years before a suitable donor heart is found. Recent studies indicate that some transplant candidates improve during this waiting period through drug treatment and other therapy, and can be removed from the transplant list.
Transplant candidates who do not improve sometimes need mechanical pumps, which are attached to the heart. Called left ventricular assist devices (LVADs), the machines take over part or virtually all of the heart's blood-pumping activity. However, current LVADs are not permanent solutions for heart failure but are considered bridges to transplantation.
An experimental surgical procedure for severe heart failure is available at a few U.S. medical centers. The procedure, called cardiomyoplasty, involves detaching one end of a muscle in the back, wrapping it around the heart, and then suturing the muscle to the heart. An implanted electric stimulator causes the back muscle to contract, pumping blood from the heart.
Also, the list provides the full range of possible side effects for these drugs. Not all patients will develop these side effects. If you suspect that you are having a side effect, alert your physician.
As heart failure progresses, the effects can become quite severe, and patients often lose the ability to perform even modest physical activity. Eventually, the heart's reduced pumping capacity may interfere with routine functions, and patients may become unable to care for themselves. The loss in functional ability can occur quickly if the heart is further weakened by heart attacks or the worsening of other conditions that affect heart failure, such as diabetes and coronary heart disease.
Heart failure patients also have an increased risk of sudden death, or cardiac arrest, caused by an irregular heartbeat.
To improve the chances of surviving with heart failure, patients must take care of themselves.
The best defense against heart failure is the prevention of heart disease. Almost all of the major coronary risk factors can be controlled or eliminated: smoking, high cholesterol, high blood pressure, diabetes, and obesity.
It helps to prepare a list of important questions. Use the spaces below to list questions you want answered. Then take this fact sheet with you to your appointment so you can record the answers.
Before you leave the doctor's office, be sure you understand your condition and its treatment, including any medications.
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