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Article title: NINDS Alzheimer's Disease Information Page: NINDS
Conditions: Alzheimer's Disease
Is there any
There is no cure for AD and no way to slow the progression of the disease. For some people in the early or middle stages of the disease, medication such as tacrine may alleviate some cognitive symptoms. Aricept (donepezil) and Exelon (rivastigmine) are reversible acetylcholinesterase inhibitors that are indicated for the treatment of mild to moderate dementia of the Alzheimer's type. Also, some medications may help control behavioral symptoms such as sleeplessness, agitation, wandering, anxiety, and depression. These treatments are aimed at making the patient more comfortable.
What is the prognosis?
AD is a progressive disease. The course of the disease varies from person to person. Some people have the disease only for the last 5 years of life, while others may have it for as many as 20 years. The most common cause of death in AD patients is infection.
What research is being
The NINDS conducts and supports research on neurodegenerative and dementing disorders, including AD. For example, although the cause of AD is still unknown, new research has shown that a vaccine, aimed at preventing or reversing the formation of AD-associated pathologic lesions, might be a useful therapy. Recent results using a transgenic mouse model suggest that immunological interventions may retard and even reverse the development of some of the pathologic changes associated with AD. Early clinical trials to test the vaccine are still in progress but offer hope for a future therapy. The National Institute on Aging and the National Institute of Mental Health also support research related to AD.
Alzheimer's Disease Education and Referral Center
P.O. Box 8250
Silver Spring, MD 20907-8250
Tel: 301-495-3311 800-438-4380
919 North Michigan Avenue
Chicago, IL 60611-1676
Tel: 312-335-8700 800-272-3900
Family Caregiver Alliance
690 Market Street
San Francisco, CA 94104
Tel: 415-434-3388 800-445-8106
Multi-infarct dementia information sheet compiled by the National Institute of Neurological Disorders and Stroke (NINDS).
Dementia With Lewy Bodies information sheet compiled by NINDS, the National Institute of Neurological Disorders and Stroke.
Myoclonus fact sheet compiled by the National Institute of Neurological Disorders and Stroke (NINDS).
Creutzfeldt-Jakob Disease (CJD) fact sheet compiled by the National Institute of Neurological Disorders and Stroke (NINDS).
Lay-language descriptions of new program announcements and clinical trials seeking patient volunteers.
This fact sheet is in the public domain. You may copy it.
The National Institute of Neurological Disorders and Stroke
National Institutes of Health
Bethesda, MD 20892
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