Have a symptom?
See what questions
a doctor would ask.
Articles » NINDS Miller Fisher Syndrome Information Page: NINDS

NINDS Miller Fisher Syndrome Information Page: NINDS

Article title: NINDS Miller Fisher Syndrome Information Page: NINDS

Main condition: Miller Fisher syndrome

Conditions: Miller Fisher syndrome

What is Miller Fisher Syndrome?
Miller Fisher syndrome is a rare, acute polyneuropathy characterized by ataxia (abnormal muscle coordination), ophthalmoplegia (paralysis of the eye muscles), and areflexia (absence of the reflexes). The disorder is a variant of Guillain-Barre syndrome. Symptoms may be preceded by a viral illness and include generalized muscle weakness and respiratory failure as in Guillain-Barre syndrome. The majority of individuals with Miller Fisher syndrome have a unique antibody that characterizes the disorder.

Is there any treatment?
Treatment for Miller Fisher syndrome is identical to treatment for Guillain-Barre syndrome: intravenous immunoglobulin (IVIg) or plasmapheresis (a procedure in which antibodies are removed from the blood) and supportive care.

What is the prognosis?
The prognosis for most individuals with Miller Fisher syndrome is good. In most cases, recovery begins within 2 to 4 weeks of the onset of symptoms, and may be almost complete within 6 months. Some individuals are left with residual deficits. Very rarely (in less than 3 percent of cases) relapses may occur.

What research is being done?
The NINDS supports research aimed at discovering new ways to diagnose, treat, and, ultimately, cure neuropathies such as Miller Fisher syndrome.


Guillain-Barre Syndrome Foundation International
P.O. Box 262
Wynnewood, PA 19096
Tel: 610-667-0131
Fax: 610-667-7036

Related NINDS Publications and Information

  • NINDS Guillain-Barre Syndrome Information Page
    No Description Available at This Time
  • Guillain-Barrč Syndrome Fact Sheet
    No Description Available at This Time
  • El Síndrome de Guillain-Barré
    No Description Available at This Time

    This fact sheet is in the public domain. You may copy it.Provided by:
    The National Institute of Neurological Disorders and Stroke
    National Institutes of Health
    Bethesda, MD 20892


    By using this site you agree to our Terms of Use. Information provided on this site is for informational purposes only; it is not intended as a substitute for advice from your own medical team. The information on this site is not to be used for diagnosing or treating any health concerns you may have - please contact your physician or health care professional for all your medical needs. Please see our Terms of Use.

    Home | Symptoms | Diseases | Diagnosis | Videos | Tools | Forum | About Us | Terms of Use | Privacy Policy | Site Map | Advertise