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Articles » Polycystic Kidney Disease: NWHIC

Polycystic Kidney Disease: NWHIC

Article title: Polycystic Kidney Disease: NWHIC

Conditions: Polycystic Kidney Disease, Autosomal dominant PKD, Autosomal recessive PKD, Acquired cystic kidney disease

Source: NWHIC


What is polycystic kidney disease?
What are the different types of polycystic kidney disease (PKD)?

See also...

What is polycystic kidney disease?

Polycystic kidney disease (PKD) is a genetic disorder characterized by the growth of numerous cysts in the kidneys. The cysts are filled with fluid. PKD cysts can slowly replace much of the mass of the kidneys, reducing kidney function and leading to kidney failure. The kidneys filter wastes from the blood to form urine. They also regulate amounts of certain vital substances in the body.

When PKD causes kidneys to fail-which usually happens only after many years-the patient requires dialysis or kidney transplantation. About one-half of people with the major type of PKD progress to kidney failure, i.e., end-stage renal disease (ESRD).

PKD can cause cysts in the liver and problems in other organs, such as the heart and blood vessels in the brain. These complications help doctors distinguish PKD from the usually harmless "simple" cysts that often form in the kidneys in later years of life.

What are the different types of polycystic kidney disease (PKD)?

There are three different types of PKD, which vary according to the way people can get the different forms. One of the inherited forms is domininant, meaning that those who have the gene from either their mother or father, will have the disease. The other inherited form, which is recessive, only develops in those individuals who have copies of the gene from both parents; otherwise, they carry the gene and may pass it to their children, but they themselves may not have kidney disease.

Autosomal dominant PKD is the most common, inherited form. Symptoms usually develop between the ages of 30 and 40, but they can begin earlier, even in childhood. About 90 percent of all PKD cases are autosomal dominant PKD.

Autosomal recessive PKD is a rare, inherited form. Symptoms of autosomal recessive PKD begin in the earliest months of life, even in the womb.

Acquired cystic kidney disease (ACKD) develops in association with long-term kidney problems, especially in patients who have kidney failure and who have been on dialysis for a long time. Therefore it tends to occur in later years of life. It is not an inherited form of PKD.

For More Information...

You can find out more about kidney stones and kidney disease by contacting the following organizations:

Prevention and Treatment of Kidney Stones 800-644-6627

Understanding Kidney Stones...Management for a Lifetime 800-333-3032

American Foundation for Urologic Disease 800-242-2383

National Kidney Foundation 800-622-9010

National Kidney and Urologic Diseases Information Clearinghouse

Oxalosis and Hyperoxaluria Foundation 800-484-9698 ext: 5100

American Kidney Fund

You can find out more information about hyperparathyroidism by contacting the following organizations:

National Institute of Diabetes and Digestive and Kidney Diseases

You can find out more information about gout by contacting the following organizations:

National Arthritis and Musculoskeletal and Skin Diseases Information Clearinghouse
9000 Rockville Pike
Bethesda, MD 20892
(301) 495-4484

International Society of Nephrology
Department of Nephrology
University of Florida
P.O. Box 100224
Gainesville, Florida 32610-0231
(904) 392-4008

International Society for Peritoneal Dialysis
c/o James F. Winchester, M.D.
Georgetown University School of Medicine
3800 Reservoir Road, NW
Washington, DC 20007
(202) 784-3662

Intersociety Council for Research for the Kidney and Urinary Tract
Northwestern University
Children's Memorial Hospital
2300 Children's Plaza
Mail Stop #37
Chicago, IL 60614

Interstitial Cystitis Association
P.O. Box 1553
Madison Square Station
New York, New York 10159
(800) ICA-1626 or (212) 979-6057
FAX (212) 677-6139

National Association for Continence (Formerly; Help for Incontinent People, Inc.)
P.O. Box 8306
Spartanburg, South Carolina 29305-8306
(803) 579-7900 or (800) BLADDER

National Association of Nephrology Technologists and Technicians
11 West Monument Avenue
Suite 510
Dayton, OH 45402
(513) 223-9765

National Organization for Rare Disorders (NORD)
P.O. Box 8923
New Fairfield, Connecticut 06812-8923
(800) 999-6673 or (203) 746-6518

North American Society for Dialysis and Transplantation
6550 Fannin
Suite 1273
Houston, Texas 77030
(713) 790-3275

North American Transplant Coordinators
P.O Box 15384
Lenexa, Kansas 66285-5384
(913) 492-3600

Organ Transplant Fund
1027 South Yates Road
Memphis, Tennessee 38119
(800) 489-3863 or (901) 684-1697

Polycystic Kidney Research Foundation

The Prostatitis Foundation

Psychonephrology Foundation
c/o New York Medical College
Psychiatric Institute
Valhalla, New York 10595
(914) 285-8424

Renal Physicians Association
2011 Pennsylvania Avenue, NW
Suite 800
Washington, DC 20006-1808
(202) 835-0436

The Simon Foundation for Continence
P.O. Box 815
Wilmette, Illinois 60091
(800) 23-SIMON

Society of Government Service Urologists
7027 Weathered Post
San Antonio, Texas 78238
(210) 681-0587

Society for Pediatric Urology
100 UCLA Medical Plaza
Los Angeles, California 90095
(310) 825-6865

Society of Urologic Nurses and Associates
East Holly Avenue
Box 56
Pitman, NJ 08071-0056
(609) 256-2335
Fax: (609) 589-7463

The Transplant Foundation
8002 Discovery Drive
Suite 310
Richmond, Virginia 23229
(804) 285-5115
FAX (804) 288-2408

Transplant Society
University Hospital-SUNY at Stony Brook
Department of Surgery - Health Science Center
T-19, Room 040
Stony Brook, New York 11794-8192

United Network for Organ Sharing (UNOS)
1100 Boulders Parkway
Suite 500
P.O. Box 13770
Richmond, Virginia 23225
(800) 24-DONOR or (804) 330-8500

United Ostomy Association
36 Executive Park
Suite 120
Irvine, California 92714
(800) 826-0826 or (714) 660-8624

Urodynamics Society
Department of Urology
200 First Street, SW
Rochester, MN 55905
(507) 284-2248

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Publication date: 1998



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