Have a symptom?
See what questions
a doctor would ask.
Diseases » Bile Duct Cancer » Wikipedia

Bile Duct Cancer in Wikipedia

Note:Wikipedia is a user-contributed encyclopedia and may not have been reviewed by professional editors (See full Wikipedia disclaimer)

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Cholangiocarcinoma". (Source - Retrieved 2006-09-07 13:55:33 from

On this Page:


Cholangiocarcinoma is an adenocarcinoma of the biliary duct system. It is a rare cancer with an incidence of 1-2:100,000. Its risk factors may include environmental exposures such as polyvinyl chloride or Thorotrast (thorium dioxide); however, this is controversial. It is also associated with the parasite opisthorchis viverrini and clonorchiasis - liver fluke. Other risk factors include hepatolithiasis, congenital liver disorders, thorotrast and ulcerative colitis - commonly when associated with primary sclerosing cholangitis. It is NOT associated with hepatitis B or liver cirrhosis.

Cholangiocarcinoma is considered curable only by surgical resection, and very often the disease is discovered too late for successful surgery. Chemotherapy has traditionally been seen as largely ineffective, but the chemotherapy agent gemcitabine (Gemzar) is often prescribed. Recently, there has been some success with the GFLIP protocol (Gemzar, $5-FU$, leucovorin, irinotecan, and cisplatin or oxalyplatin), a protocol first developed and shown to be useful for pancreatic cancer.

See also


By using this site you agree to our Terms of Use. Information provided on this site is for informational purposes only; it is not intended as a substitute for advice from your own medical team. The information on this site is not to be used for diagnosing or treating any health concerns you may have - please contact your physician or health care professional for all your medical needs. Please see our Terms of Use.

Home | Symptoms | Diseases | Diagnosis | Videos | Tools | Forum | About Us | Terms of Use | Privacy Policy | Site Map | Advertise