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Diseases » Canavan disease » Summary
 

What is Canavan disease?

What is Canavan disease?

  • Canavan disease: Rare genetic degenerative brain disease in infants.

Canavan disease is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that Canavan disease, or a subtype of Canavan disease, affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)

Ophanet, a consortium of European partners, currently defines a condition rare when it affects 1 person per 2,000. They list Canavan disease as a "rare disease".
Source - Orphanet

Canavan disease: Introduction

Types of Canavan disease:

Broader types of Canavan disease:

How many people get Canavan disease?

Prevalance of Canavan disease: 1 per 6,400 - 13,500 people of Ashkenazi Jewish heritage suffer from Canavan disease, Genetics Home Reference website
Prevalance Rate of Canavan disease: approx 1 in 6,400 or 0.02% or 42,500 people in USA [about data]

Who gets Canavan disease?

Patient Profile for Canavan disease: Infancy. Symptoms appear early.

Profile for Canavan disease: Although Canavan disease may occur in any ethnic group, it affects persons of Eastern European Jewish ancestry more frequently. (Source: excerpt from NINDS Canavan Disease Information Page: NINDS)

How serious is Canavan disease?

Prognosis of Canavan disease: Poor. Degenerative. Typically death before age 10.
Complications of Canavan disease: see complications of Canavan disease
Prognosis of Canavan disease: The prognosis for Canavan disease is poor. Death usually occurs before age 10. (Source: excerpt from NINDS Canavan Disease Information Page: NINDS)

What causes Canavan disease?

Causes of Canavan disease: see causes of Canavan disease
Risk factors for Canavan disease: see risk factors for Canavan disease

What are the symptoms of Canavan disease?

Symptoms of Canavan disease: see symptoms of Canavan disease

Complications of Canavan disease: see complications of Canavan disease

Can anyone else get Canavan disease?

Contagion of genetic conditions: generally not; see details in contagion of genetic diseases.

Inheritance of genetic conditions: see details in inheritance of genetic diseases.

Canavan disease: Testing

Diagnostic testing: see tests for Canavan disease.

Misdiagnosis: see misdiagnosis and Canavan disease.

How is it treated?

Treatments for Canavan disease: see treatments for Canavan disease
Research for Canavan disease: see research for Canavan disease

Organs Affected by Canavan disease:

Organs and body systems related to Canavan disease include:

Name and Aliases of Canavan disease

Main name of condition: Canavan disease

Class of Condition for Canavan disease: genetic

Other names or spellings for Canavan disease:

Canavan-van Bogaert-Bertrand disease, Spongy degeneration of the central nervous system, Von Bogaert-Bertrand disease, Aspartoacylase deficiency, ASPA deficiency, ASP deficiency, ACY2 deficiency, Aminoacylase 2 deficiency, Spongy degeneration of central nervous system

ACY2 deficiency, ASP deficiency, ASPA deficiency, Aminoacylase 2 deficiency, Aspartoacylase deficiency, Canavan leukodystrophy, Canavan-van Bogaert-Bertrand disease, Spongy degeneration of the brain, Spongy degeneration of the central nervous system, Von Bogaert-Bertrand disease
Source - Office of Rare Diseases (ORD) of the National Institutes of Health (NIH)

Canavan disease: Related Conditions

Research the causes of these diseases that are similar to, or related to, Canavan disease:

 

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