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Glossary for Charcot-Marie-Tooth disease, Type 4G

  • Charcot-Marie-Tooth disease, Type 4H: CMT is an inherited neurological disease characterized by the gradual degeneration of nerves which starts in the hands and feet and results in progressive numbness, muscle weakness and loss of function. Type 4H has an autosomal recessive form of inheritance and involves a defect on Chromosome 11.
  • Degenerative conditions: Diseases characterized by a progressive and degenerative decline.
  • Dizziness: Feelings of lightheadedness or giddiness.
  • Foot drop: A condition which is characterized by the dropping of the foot due to a paralysis of the anterior muscles of the leg
  • Foot weakness: A decrease in the usual strength of the movements of the foot
  • Genetic Disease: Any disease that is handed down to oneself through the chromosomes of ones parents
  • Hand weakness: Weakness of one or both hands
  • High foot arches: High foot arches are unusually high arches of the feet.
  • Limb conditions: Medical conditions affecting the upper or lower limbs.
  • Movement disorders: Medical conditions affecting the movement systems, such as walking or tremor.
  • Muscle conditions: Any condition that affects the muscles of the body
  • Musculoskeletal conditions: Medical conditions affecting the musculoskeletal system of bones, muscles and related structures.
  • Nervous system conditions: Diseases affecting the nerves and the nervous system.
  • Neuromuscular conditions: Conditions affecting the nerve-muscle systems.
  • Neuropathy: Peripheral neuropathy is the term for damage to nerves of the peripheral nervous system, which may be caused either by diseases of the nerve or from the side-effects of systemic illness.
  • Sensory conditions: Medical conditions affecting the sensory system, especially the sense of touch.
  • Toe symptoms: Symptoms affecting the toes
  • Wasted foot muscles: Wasted foot muscles refers to foot muscles that have shrunken and have become weak.
  • Wasted hand muscles: Wasted hand muscles are hand muscles that have shrunken and have become weak.


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