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Chronic myeloid leukemia

Chronic myeloid leukemia: Introduction

Chronic myeloid leukemia: Chronic myeloid leukemia (CML) is a cancer of blood cells, characterized by replacement of the bone marrow with malignant, leukemic cells. Many of these ... more about Chronic myeloid leukemia.

Chronic myeloid leukemia: Type of leukemia mostly in adults; rarely in children. More detailed information about the symptoms, causes, and treatments of Chronic myeloid leukemia is available below.

Symptoms of Chronic myeloid leukemia

Treatments for Chronic myeloid leukemia

  • Tyrosinase kinase inhibitors - Imatinib, Dasatinib, and Nilotinib. Imatinib is the first line therapy for many people, and those unsuitable for stem cell transplantation
  • Stem Cell transplantation- peripheral or bone marrow
  • Chemotherapy - used when tyrosine kinase inhibitors stop working or with stem cell transplantation
  • Interferon - used when other drugs don't work, or when they can't be used, such as in pregnancy
  • Radiotherapy - rarely used to shrink splenomegaly or treat enlarged nodes
  • more treatments...»

Home Diagnostic Testing

Home medical testing related to Chronic myeloid leukemia:

Wrongly Diagnosed with Chronic myeloid leukemia?

Chronic myeloid leukemia: Related Patient Stories

Chronic myeloid leukemia: Deaths

Read more about Deaths and Chronic myeloid leukemia.

Chronic myeloid leukemia: Complications

Review possible medical complications related to Chronic myeloid leukemia:

Causes of Chronic myeloid leukemia

Read more about causes of Chronic myeloid leukemia.

Disease Topics Related To Chronic myeloid leukemia

Research the causes of these diseases that are similar to, or related to, Chronic myeloid leukemia:

Chronic myeloid leukemia: Undiagnosed Conditions

Commonly undiagnosed diseases in related medical categories:

Misdiagnosis and Chronic myeloid leukemia

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Whooping cough often undiagnosed: Although most children in the Western world have been immunized against whooping cough (also called "pertussis"), this protection more »

Spitz nevi misdiagnosed as dangerous melanoma skin cancer: One possible misdiagnosis to consider in lieu of melanoma is spitz nevi. See melanoma and more »

Chronic myeloid leukemia: Research Doctors & Specialists

Research related physicians and medical specialists:

Other doctor, physician and specialist research services:

Hospitals & Clinics: Chronic myeloid leukemia

Research quality ratings and patient safety measures for medical facilities in specialties related to Chronic myeloid leukemia:

Choosing the Best Hospital: More general information, not necessarily in relation to Chronic myeloid leukemia, on hospital performance and surgical care quality:

Chronic myeloid leukemia: Rare Types

Rare types of diseases and disorders in related medical categories:

Evidence Based Medicine Research for Chronic myeloid leukemia

Medical research articles related to Chronic myeloid leukemia include:

Click here to find more evidence-based articles on the TRIP Database

Chronic myeloid leukemia: Animations

Prognosis for Chronic myeloid leukemia

Research about Chronic myeloid leukemia

Visit our research pages for current research about Chronic myeloid leukemia treatments.

Statistics for Chronic myeloid leukemia

Chronic myeloid leukemia: Broader Related Topics

Chronic myeloid leukemia Message Boards

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User Interactive Forums

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Article Excerpts about Chronic myeloid leukemia

Chronic myeloid leukemia (CML) is a cancer of blood cells, characterized by replacement of the bone marrow with malignant, leukemic cells. Many of these leukemic cells can be found circulating in the blood and can cause enlargement of the spleen, liver, and other organs. (Source: Genes and Disease by the National Center for Biotechnology)

Definitions of Chronic myeloid leukemia:

The most common chronic myeloproliferative disorder characterized by neutrophilic leukocytosis. It is associated with the Philadelphia (Ph) chromosome and/or the BCR/ABL fusion gene. Most patients are middle-aged or elderly. Common findings at presentation include fatigue, weight loss, anemia, night sweats, and splenomegaly. The disease is bi- or triphasic: an initial indolent chronic phase is followed by accelerated or blast phase. Allogeneic bone marrow transplantation is currently the only curative therapy (adapted from WHO 2001). -- 2003 - (Source - Diseases Database)

Chronic myeloid leukemia is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that Chronic myeloid leukemia, or a subtype of Chronic myeloid leukemia, affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)

Ophanet, a consortium of European partners, currently defines a condition rare when it affects 1 person per 2,000. They list Chronic myeloid leukemia as a "rare disease".
Source - Orphanet


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