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Diseases » Colorectal cancer » Summary

What is Colorectal cancer?

What is Colorectal cancer?

Colorectal cancer is a cancer that grows within the colon, also called the large intestine. A cancer that grows in the last section ...more »

  • Colorectal cancer: Cancer of the colon (bowel) or rectum.
  • Colorectal cancer: Colorectal carcinoma is a disease of Western-world lifestyle. Among both males and females, it is the second most common visceral malignancy in the United States, with an expected 185,000 new cases each year. Grossly, most colorectal carcinomas are either polypoid or of the ulcerative -infiltrating type. Adenocarcinoma is the most common carcinoma in the colon and rectum. Colorectal adenocarcinoma can be divided in three grades: Grade I (low grade or well-differentiated), grade II (average grade or moderately differentiated) and grade III (poorly differentiated). The following histopathologic features have been shown to be prognostic indicators in multivariate analysis: microacinar versus macroacinar growth pattern, endocrine cells detected by chromogranin immunohistochemistry, Crohn's-like reaction and tumor budding. The standard therapy for colorectal carcinoma is surgical resection. The 5-year crude survival rate after curative resection for colorectal carcinomas ranges between 40% and 60% in most large series (Sternberg's Diagnostic Surgical Pathology, 3rd ed., 1999). --2002
    Source - Diseases Database
  • Colorectal cancer: a malignant tumor of the colon; early symptom is bloody stools.
    Source - WordNet 2.1

Colorectal cancer: Introduction

Types of Colorectal cancer:

Types of Colorectal cancer:

  • Stages of colorectal cancer:
    • Stage 0 colorectal cancer - very early cancer of the lining.
    • Stage I colorectal cancer - involving the inner wall of colon or rectum.
    • Stage II colorectal cancer - cancer has spread locally beyond colon/rectum but not to lymph nodes.
    • Stage III colorectal cancer - spread to lymph nodes but not further.
    • Stage IV colorectal cancer - metastatic cancer; usually to liver or lungs.
  • Recurrent colorectal cancer - occurring again after previous treatment.
  • more types...»

Broader types of Colorectal cancer:

How many people get Colorectal cancer?

Incidence (annual) of Colorectal cancer: 148,300 annual cases = 107,300 annual cases of colon cancer and 41,000 annual cases of rectum cancer(SEER 2002 estimate)
Incidence Rate of Colorectal cancer: approx 1 in 1,834 or 0.05% or 148,300 people in USA [about data]
Lifetime risk of Colorectal cancer: 1 in 26 women and 1 in 17 men will develop colorectal cancer during their lifetime in Australia 2000 (AIHW and AACR, AIHW National Mortality Database, Australia’s Health 2004, AIHW)
Prevalance of Colorectal cancer: The American Cancer Society estimates that there will be 93,800 new cases of colon cancer diagnosed in the US in 2000, with 47,700 resulting deaths. (Source: Genes and Disease by the National Center for Biotechnology)

Who gets Colorectal cancer?

Patient Profile for Colorectal cancer: Typically over 50's but any age possible.

Profile for Colorectal cancer: It is found most often in people aged 50 and older. (Source: excerpt from Colorectal Cancer: NWHIC)

Gender Profile for Colorectal cancer: It is a myth that this cancer affects mostly men. Women get colorectal cancer as often as men do (about a 1 in 20 chance). (Source: excerpt from Colorectal Cancer: NWHIC)

How serious is Colorectal cancer?

Complications of Colorectal cancer: see complications of Colorectal cancer
Survival rate for Colorectal cancer: 47% survival rate for colon cancer in the UK 2001 (National Statistics – UK Government Census, 2001)
Average life years lost for Colorectal cancer: 13.4 years for colon/rectum cancer (SEER)1
Deaths for Colorectal cancer: 57,200 deaths in USA 1999 (CDC)

What causes Colorectal cancer?

Causes of Colorectal cancer: see causes of Colorectal cancer
Causes of Colorectal cancer: All kinds of cancer occur when cell division, normally a very highly regulated process, gets out of control. While environmental factors can certainly contribute to a person's risk of cancer (e.g. smoking, diet, and exercise), most cancers have a genetic basis too. Literally hundreds of genes and proteins are involved in monitoring the process of cell division and DNA replication; a mutation in one or more of these genes or proteins can sometimes lead to uncontrolled cancerous growth. (Source: Genes and Disease by the National Center for Biotechnology)
Risk factors for Colorectal cancer: see risk factors for Colorectal cancer

What are the symptoms of Colorectal cancer?

Symptoms of Colorectal cancer: see symptoms of Colorectal cancer

Complications of Colorectal cancer: see complications of Colorectal cancer

Can anyone else get Colorectal cancer?

Contagion of cancer: generally not; see details in contagion of cancer.
Inheritance: see inheritance of Colorectal cancer

Colorectal cancer: Testing

Diagnostic testing: see tests for Colorectal cancer.

Misdiagnosis: see misdiagnosis and Colorectal cancer.

How is it treated?

Doctors and Medical Specialists for Colorectal cancer: Gastroenterologist, Surgeon, Medical oncologist, Radiation oncologist ; see also doctors and medical specialists for Colorectal cancer.
Treatments for Colorectal cancer: see treatments for Colorectal cancer
Alternative treatments for Colorectal cancer: see alternative treatments for Colorectal cancer
Prevention of Colorectal cancer: see prevention of Colorectal cancer
Research for Colorectal cancer: see research for Colorectal cancer

Society issues for Colorectal cancer

Hospitalization statistics for Colorectal cancer: The following are statistics from various sources about hospitalizations and Colorectal cancer:

  • 0.75% (95,420) of hospital consultant episodes were for malignant neoplasm of colon in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
  • 92% of hospital consultant episodes for malignant neoplasm of colon required hospital admission in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
  • 55% of hospital consultant episodes for malignant neoplasm of colon were for men in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
  • 45% of hospital consultant episodes for malignant neoplasm of colon were for women in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
  • more statistics...»

Organs Affected by Colorectal cancer:

Organs and body systems related to Colorectal cancer include:

Name and Aliases of Colorectal cancer

Main name of condition: Colorectal cancer

Class of Condition for Colorectal cancer: cancer

Other names or spellings for Colorectal cancer:

Colon Cancer, Bowel cancer, Colorectal tumor, Cancer of the colon and rectum, Bowel tumor, Colon tumor, Rectal cancer

Colonic or rectal adenocarcinoma, Colorectal carcinoma, Large bowel cancer Source - Diseases Database

Colorectal cancer: Related Conditions

Research the causes of these diseases that are similar to, or related to, Colorectal cancer:

1. SEER Cancer Statistics Review 1975-2000, National Cancer Institute (NCI)

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