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Glossary for Colorectal Cancer, Susceptibility to, 8

  • Abdominal conditions: Medical conditions affecting the abdominal region.
  • Aging: The medical conditions from getting older.
  • Alcohol -- Teratogenic Agent: There is strong evidence to indicate that exposure to Alcohol during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the level of exposure and the stage of pregnancy that the exposure occurred at.
  • Altered bowel habit: An altered bowel habit is any abnormal unusual bowel movement or change in the normal pattern of bowel movements in an individual.
  • Anorectal disorders: Conditions that affect the anorectum
  • Cancer: Abnormal overgrowth of body cells.
  • Colorectal Cancer, Susceptibility to, 1: Colorectal cancer refers to cancer of the colon (bowel) or cancer of the rectum, depending on the region affected. It is an under-diagnosed condition because it has no early symptoms. Even when symptoms occur, both the symptoms and the diagnostic tests required are considered embarrassing by many, leading to delayed diagnosis. However, early diagnosis is crucial as colon cancer is a leading cause of death. There are various genes which are linked to an increased risk of developing colorectal cancer. Not all patients with the genetic defect will develop colorectal cancer but the presence of additional triggering factors such as alcohol may trigger the development in those genetically susceptible. Type 1 is linked to a defect on chromosome 9.
  • Constipation: Difficult or dry bowel movements
  • Diabetes: Failing or reduced ability of the body to handle sugars.
  • Diarrhea: Loose or watery stool.
  • Digestive Diseases: Diseases that affect the digestive system
  • Gastrointestinal tumors: Any tumor of the gastrointestinal (digestive) system, including cancers and benign tumors.
  • Inflammatory bowel disease: Inflammatory bowel disease refers to digestive symptoms resulting from chronic bowel inflammation. Crohn's disease and ulcerative colitis are two of the main subtypes of the disease. Scientists have discovered an array of genetic mutations which can result in an increased susceptibility to inflammatory bowel disease. Not all people with the genetic anomaly will develop the condition but it can increase the risk especially if other environmental factors are also present. The severity of the disease that develops is variable.
  • Intestinal Conditions: Conditions that affect the intestines
  • Metastatic cancer: Any cancer that has spread to other parts of the body.
  • No symptoms: The absence of noticable symptoms.
  • Obesity: An increase in the body weight greater than that required for normal function that is characterised by the accumulation of excessive fat
  • Smoking: The smoking of cigarettes


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