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Diagnosis Mistakes » Blindness in Tuberculosis could be drug- induced

Blindness in Tuberculosis could be drug- induced

Pulmonary tuberculosis is the infection of lung caused by the organism called Mycobacterium tuberculosis. The involvement of the lungs is the most common presentation. Tuberculosis spreads through the blood, lymph and reaches others parts of the body easily, infecting it. The primary form of the disease maybe asymptomatic or symptomatic. Patients with TB have increased risk in developing HIV infection. The condition maybe be misdiagnosed with fever of unknown origin. The diagnosis is usually made on chest x-ray and sputum culture. The treatment commonly known as DOTS (directly observed therapy) includes administration of four antibiotic drugs namely isoniazid, rifampicin, ethambutol, and streptomycin. Ethambutol is noted to cause colour blindness, decreased vision, central scotoma known as optic neuritis and liver toxicity. With discontinuation of the drug patient see an improvement in the vision.

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