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Cushing’s syndrome usually occurs due to chronic steroid administration, bilateral adrenal hyperplasia, adrenal tumour and ACTH excess. Morbidity and mortality associated with Cushing syndrome are related primarily to the effects of excess glucocorticoids. The patient usually presents to the doctor with features of weight gain more so on the face with skin changes, depression and muscle weakness. A proper history is needed to rule out conditions like obesity, bulimia, alcoholism and depression.
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