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Infectious mononucleosis must be considered in 15- 25 year old patients presenting with a painful throat. The patient presents with slow onset of malaise, fever, headache sore throat and rash. It can be misdiagnosed as HIV primary infection, tonsillitis, viral hepatitis and leukaemia. Paul Bunnell test is one of the important lab tests commonly done along with white cell count and blood smear. There is no specific treatment and supportive measures will suffice. It usually runs an uncomplicated course.
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