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Diseases » Foot ulcer » Glossary

Glossary for Foot ulcer

  • Alcoholism: Alcoholism is the compulsive urge to drink alcohol despite knowing the negative impact on one's health.
  • Atherosclerosis: Atherosclerosis is a syndrome affecting arterial blood vessels. It is a chronic inflammatory response in the walls of arteries, in large part due to the accumulation of macrophage white blood cells and promoted by low density (especially small particle) lipoproteins (plasma proteins that carry cholesterol and triglycerides) without adequate removal of fats and cholesterol from the macrophages by functional high density lipoproteins (HDL). It is commonly referred to as a hardening or furring of the arteries. It is caused by the formation of multiple plaques within the arteries.
  • Blastomycosis: A fungal infection caused by Blastomyces dermatitidis and resulting in lung, skin, bone and genitourinary involvement.
  • Bleeding symptoms: Any type of bleeding symptoms.
  • Buerger's disease: Buergers's disease is a recurring inflammation and thrombosis (clotting) of small and medium arteries and veins of the hands and feet
  • Cancer: Abnormal overgrowth of body cells.
  • Cervical hypertrichosis -- peripheral neuropathy: A rare genetic disorder characterized by excessive body hair at birth and peripheral neuropathy.
  • Charcot-Marie-Tooth disease, Type 2B: CMT is an inherited neurological disease characterized by the gradual degeneration of nerves which starts in the hands and feet and results in progressive numbness, muscle weakness and loss of function. Type 2B has an autosomal dominant inheritance and involves a defect in the gene for the protein RAB 7 located on chromosome 3.
  • Circulatory disorder: Disease affecting circulation of blood
  • Diabetes: Failing or reduced ability of the body to handle sugars.
  • Diabetic Peripheral Neuropathy: Diabetic nerve damage affecting toes, feet, and sometimes hands.
  • Familial amyloid polyneuropathy: A rare inherited condition where impaired nerve function is caused by amyloid deposits in peripheral nerves.
  • Foot conditions: Any condition that may affect the foot
  • Foot injury: Any injury to the foot
  • Foot pain: Pain affecting one or both feet
  • Foot swelling: Oedema of the foot.
  • Fungal infections: Any condition caused by fungus.
  • Hypertrophic neuropathy of Dejerine-Sottas: An inherited neurological disease characterized by the gradual degeneration of nerves which starts in the hands and feet and results in numbness, muscle weakness and loss of function. The severity of the condition is variable.
  • Ischemia: Inadequate blood supply to tissues, usually caused by a problem in the blood vessel.
  • Leprosy: A chronic, progressive infectious disease caused by Mycobacterium leprae which causes skin sores and also affects the eyes, mucous membranes and peripheral nerves.
  • Limb conditions: Medical conditions affecting the upper or lower limbs.
  • Lower limb conditions: Any medical condition affecting the lower limbs, i.e. the legs, knees, feet, etc..
  • Neuropathy: Peripheral neuropathy is the term for damage to nerves of the peripheral nervous system, which may be caused either by diseases of the nerve or from the side-effects of systemic illness.
  • Neuropathy sensory spastic paraplegia: A very rare syndrome characterized mainly by sensory nerve degeneration and spastic paraplegia. The extremities of the hands and feet have reduced pain sensation and disfiguring ulcers tend to develop.
  • Neuropathy, hereditary, sensory, radicular: A rare inherited degenerative disorder of the nervous system characterized by sensory loss in limbs, pain and foot ulcers.
  • Paraplegia: Paralysis of legs and sometimes lower body
  • Peripheral neuropathy: Peripheral neuropathy is the term for damage to nerves of the peripheral nervous system, which may be caused either by diseases of the nerve or from the side-effects of systemic illness.
  • Peripheral vascular disease: Disease of arteries supplying the legs or sometimes arms
  • Portuguese type amyloidosis: An inherited form of systemic amyloidosis which involves deposits of a substance called amyloid throughout various parts of the body.
  • Raynaud's phenomenon: Blood vessel constriction attacks affecting fingers and/or toes.
  • Sickle Cell Anemia: Sickle cell anemia is an inherited blood disorder characterized by red blood cells which are crescent-shaped rather than the normal doughnut shape. These abnormally shaped red blood cells are unable to function normally and tend to undergo premature destruction which leads to anemia. If the genetic defect which causes the condition is inherited from both parents the condition can be quite severe whereas if it is inherited from only one parent, often there are no symptoms. The abnormally shaped red blood cells can cause problems when they clump together and block blood vessels.
  • Skin conditions: Any condition that affects the skin
  • Sporotrichosis: A fungal skin infection caused by the fungus Sporothrix schenckii. Usually only the skin is infected but bones, lungs and central nervous system can rarely be affected also. Transmission usually occurs through infection of a skin wound.
  • Squamous Cell Skin Cancer: Aggressive skin cancer arising due to sun exposure; lesions are locally invasive to surrounding tissues and may metastasise
  • Tingling: Tingling, prickling, or pins-and-needles sensations
  • Tumor: Any type of lump or swelling (not just cancers)
  • Type 1 diabetes: Severe insulin-treated diabetes typically occurring in young people.
  • Type 2 diabetes: Most common diabetes in adults, usually progressing slowly, mostly treated without insulin at diagnosis.
  • Type IV Hyperlipoproteinemia: Type IV Hyperlipoproteinemia is an inherited condition characterized by high levels of very low density lipoproteins (VLDL) in the blood which in turn causes high cholesterol levels. Lipoproteins are responsible for transporting cholesterol in the bloodstream and high levels of them in the bloodstream means that there are high levels of cholesterol in the bloodstream. The high VLDL levels are a result of increased production and reduced elimination of the VLDLs. Environmental factors are the driving force behind this condition.
  • Werner syndrome: A form of premature aging where sufferers start aging during adolescence or soon after and appear old by the time they reach their 30's or 40's. Milder forms of the condition may also occur.


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