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Diseases » Graves Disease » Summary

What is Graves Disease?

What is Graves Disease?

Graves' disease is a disease of the thyroid gland. Graves' disease results in an abnormal overactivity of the thyroid gland. The ...more »

  • Graves Disease: is an autoimmune disease characterized by hyperthyroidism due to circulating autoantibodies. Thyroid-stimulating immunoglobulins (TSIs) bind to and activate thyrotropin receptors, causing the thyroid gland to grow and the thyroid follicles to increase synthesis of thyroid hormone.
  • Graves Disease: Hyperthyroidism associated with diffuse hyperplasia of the thyroid gland (goiter), resulting from production of antibodies that are directed against the thyrotropin receptor complex of the follicular epithelial cells. As a result, the thyroid gland enlarges and secrets increased amounts of thyroid hormones. --2004
    Source - Diseases Database
  • Graves Disease: exophthalmos occurring in association with goiter; hyperthyroidism with protrusion of the eyeballs.
    Source - WordNet 2.1

Graves Disease: Introduction

Types of Graves Disease:

Broader types of Graves Disease:

How many people get Graves Disease?

Prevalance of Graves Disease: 3,048,636 people in the USA 1996 1; 1.3 million people (NWHIC)
Prevalance Rate of Graves Disease: approx 1 in 89 or 1.12% or 3 million people in USA [about data]
Incidence (annual) of Graves Disease: about 5 per 10,000 people (NWHIC)
Incidence Rate of Graves Disease: approx 1 in 2,000 or 0.05% or 136,000 people in USA [about data]
Incidence of Graves Disease: The incidence is about 5 in 10,000 people. (Source: excerpt from Graves' Disease: NWHIC)

Who gets Graves Disease?

Gender Profile for Graves Disease: Women 7:1; ranges from 4:1 to 8:1 (NWHIC)

Gender Ratio for Graves Disease: female:male 8:1

How serious is Graves Disease?

Prognosis of Graves Disease: Most patients become hypothyroid and require replacement. Similarly, the ophthalmopathy generally becomes quiescent. On occasion, hyperthyroidism returns because of persisting thyroid tissue after ablation and high antibody titers of anti-TSI. Further therapy may be necessary in the form of surgery or radioactive iodine ablation.
Complications of Graves Disease: see complications of Graves Disease
Prognosis of Graves Disease: If left untreated, Graves' disease can be fatal. In most cases, however, normal health can be restored. (Source: excerpt from Endocrine Diseases: NWHIC)

What causes Graves Disease?

Causes of Graves Disease: see causes of Graves Disease
Risk factors for Graves Disease: see risk factors for Graves Disease

What are the symptoms of Graves Disease?

Symptoms of Graves Disease: see symptoms of Graves Disease

Complications of Graves Disease: see complications of Graves Disease

Onset of Graves Disease: Graves's disease is the most common cause of hyperthyroidism. Incidence in women reports a rate of 80 cases per 100,000 women per year.

Can anyone else get Graves Disease?

Contagion of autoimmunity: generally not; see details in contagion of autoimmune diseases.

Graves Disease: Testing

Diagnostic testing: see tests for Graves Disease.

Misdiagnosis: see misdiagnosis and Graves Disease.

How is it treated?

Doctors and Medical Specialists for Graves Disease: Allergist/Immunologist, Endocrinologist ; see also doctors and medical specialists for Graves Disease.
Treatments for Graves Disease: see treatments for Graves Disease
Prevention of Graves Disease: see prevention of Graves Disease
Research for Graves Disease: see research for Graves Disease

Organs Affected by Graves Disease:

Organs and body systems related to Graves Disease include:

Name and Aliases of Graves Disease

Main name of condition: Graves Disease

Class of Condition for Graves Disease: autoimmune

Other names or spellings for Graves Disease:

Graves Hyperthyroidism, Basdow's disease, Basedow disease, exophthalmic goiter, Parry disease, thyrotoxicosis, Hyperthyroid Grave's disease

Basedow's disease Source - Diseases Database

Graves' disease, Exophthalmic goiter
Source - WordNet 2.1

Graves Disease: Related Conditions

Research the causes of these diseases that are similar to, or related to, Graves Disease:

1. Rose and Mackay, 1998, The Autoimmune Diseases, Third Edition

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