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Glossary for Juvenile Paget disease

  • Angioid streaks: Streaks that radiate out from the optic nerve head under the retina. The streaks may be red, brown or grey. The streaks resemble blood vessels and hence the term angioid. The streaks represent tiny breaks in the elastic membrane of the retina (Bruch's membrane). The anomaly is often associated with conditions such as Paget's disease, sickle cell anemia, Ehlers-Danlos syndrome and pseudoxanthoma elasticum.
  • Blue sclerae: Blue colouring of the sclerae in the eye.
  • Bone conditions: Conditions that affect the bones
  • Child health conditions: Any medical conditions typically afflicting children.
  • Deafness: Inability to hear sounds.
  • Developmental problems: Physical or mental development difficulty.
  • Genu varum: The presence of bowed legs - knees are apart and ankles are together while standing. Causes of the anomaly include certain intrauterine positions, rickets and various bone disorders.
  • Kaler-Garrity-Stern syndrome: A very rare syndrome characterized mainly by osteopenia, mental retardation and sparse hair.
  • Kyphosis: Outward curvature of the spine at the back causing hunching or Dowager's hump
  • Metabolic disorders: Disorders that affect the metabolic system in human
  • Musculoskeletal conditions: Medical conditions affecting the musculoskeletal system of bones, muscles and related structures.
  • Osteoporosis: Bone thinning and weakening from bone calcium depletion.
  • Paget disease juvenile type: A rare genetic bone disorder involving abnormal loss of bone mineralization and remineralization, broadened bone shafts and high levels of alkaline phosphatase in the blood. Some juvenile cases are relatively mild.
  • Poor growth: Poor body growth or delayed physical development.
  • Sensorineural deafness: A condition which is characterized by deafness due to a sensineural deficit
  • Tooth loss: The loss of a tooth


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