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Krabbé Disease

Krabbé Disease: Introduction

Krabbé Disease: Brain myelin disorder with various symptoms. More detailed information about the symptoms, causes, and treatments of Krabbé Disease is available below.

Symptoms of Krabbé Disease

Treatments for Krabbé Disease

Home Diagnostic Testing

Home medical testing related to Krabbé Disease:

Wrongly Diagnosed with Krabbé Disease?

Krabbé Disease: Related Patient Stories

Krabbé Disease: Complications

Read more about complications of Krabbé Disease.

Causes of Krabbé Disease

Read more about causes of Krabbé Disease.

Krabbé Disease: Undiagnosed Conditions

Commonly undiagnosed diseases in related medical categories:

Misdiagnosis and Krabbé Disease

Undiagnosed stroke leads to misdiagnosed aphasia: BBC News UK reported on a man who had been institutionalized and treated for mental illness because he suffered from sudden inability to more »

Dementia may be a drug interaction: A common scenario in aged care is for a patient to show mental decline to dementia. Whereas this can, of course, occur due to various medical conditions, such as a stroke or more »

Mild traumatic brain injury often remains undiagnosed: Although the symptoms of severe brain injury are hard to miss, it is less clear for milder injuries, or even those causing a mild concussion diagnosis. The condition goes by more »

MTBI misdiagnosed as balance problem: When a person has symptoms such as vertigo or dizziness, a diagnosis of brain injury may go overlooked. This is particularly true of mild traumatic more »

Brain pressure condition often misdiagnosed as dementia: A condition that results from an excessive pressure of CSF within the brain is often misdiagnosed. It may be misdiagnosed as Parkinson's disease or dementia (such as more »

Post-concussive brain injury often misdiagnosed: A study found that soldiers who had suffered a concussive injury in battle often more »

Children with migraine often misdiagnosed: A migraine often fails to be correctly diagnosed in pediatric patients. These patients are not more »

Krabbé Disease: Research Doctors & Specialists

Research related physicians and medical specialists:

Other doctor, physician and specialist research services:

Krabbé Disease: Rare Types

Rare types of diseases and disorders in related medical categories:

Krabbé Disease: Animations

Prognosis for Krabbé Disease

Prognosis for Krabbé Disease: poor. Typically fatal by age 2.

Research about Krabbé Disease

Visit our research pages for current research about Krabbé Disease treatments.

Clinical Trials for Krabbé Disease

The US based website lists information on both federally and privately supported clinical trials using human volunteers.

Some of the clinical trials listed on for Krabbé Disease include:

Statistics for Krabbé Disease

Krabbé Disease: Broader Related Topics

Krabbé Disease Message Boards

Related forums and medical stories:

User Interactive Forums

Read about other experiences, ask a question about Krabbé Disease, or answer someone else's question, on our message boards:

Definitions of Krabbé Disease:

A degenerative disease of the central and peripheral nervous system caused by abnormal breakdown and turnover of myelin and marked by reduced galacosylceramide beta-galactosidase activity (EC Two types based on the age of onset are recognized: Infantile-onset Krabbe disease is marked by the appearance of symptoms at ages 3-6 months, which include irritability, frequent crying, and increase of muscle tonus. They are followed by opisthotonos, less of tendon reflexes, visual failure, elevated cerebrospinal fluid proteins, and delayed nerve conduction velocity. Most infants die during the second year of life. Late-onset Krabbe disease (LOKD) has first symptoms at ages 5 to 10 years, consisting of focal neurological signs, hemiparesis, cerebellar ataxia, cortical blindness, and spastic paraplegia, followed by mental and physical deterioration. Some patients survive into adulthood. - (Source - Diseases Database)

Krabbé Disease is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that Krabbé Disease, or a subtype of Krabbé Disease, affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)

Ophanet, a consortium of European partners, currently defines a condition rare when it affects 1 person per 2,000. They list Krabbé Disease as a "rare disease".
Source - Orphanet


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