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What is Landau-Kleffner Syndrome?

What is Landau-Kleffner Syndrome?

  • Landau-Kleffner Syndrome: A neurological disorder which results in aphasia, epileptic seizures and inability to recognize sounds.
  • Landau-Kleffner Syndrome: A syndrome characterized by the onset of isolated language dysfunction in otherwise normal children (age of onset 4-7 years) and epileptiform discharges on ELECTROENCEPHALOGRAPHY. Seizures, including atypical absence (EPILEPSY, ABSENCE), complex partial (EPILEPSY, COMPLEX PARTIAL), and other types may occur. The electroencephalographic abnormalities and seizures tend to resolve by puberty. The language disorder may also resolve although some individuals are left with severe language dysfunction, including APHASIA and auditory AGNOSIA. (From Menkes, Textbook of Child Neurology, 5th ed, pp749-50; J Child Neurol 1997 Nov;12(8):489-495)
    Source - Diseases Database

Landau-Kleffner Syndrome is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that Landau-Kleffner Syndrome, or a subtype of Landau-Kleffner Syndrome, affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)

Landau-Kleffner Syndrome: Introduction

Types of Landau-Kleffner Syndrome:

Broader types of Landau-Kleffner Syndrome:

How many people get Landau-Kleffner Syndrome?

Prevalance of Landau-Kleffner Syndrome: rare

Who gets Landau-Kleffner Syndrome?

Patient Profile for Landau-Kleffner Syndrome: Typically children age 3-7.

Profile for Landau-Kleffner Syndrome: The disorder usually occurs in children between the ages of 3 and 7. (Source: excerpt from NINDS Landau-Kleffner Syndrome Information Page: NINDS)

How serious is Landau-Kleffner Syndrome?

Prognosis of Landau-Kleffner Syndrome: some cases may spontaneously improve
Complications of Landau-Kleffner Syndrome: see complications of Landau-Kleffner Syndrome
Prognosis of Landau-Kleffner Syndrome: The prognosis for children with LKS varies. Some affected children may have a permanent severe language disorder, while others may regain much of their language abilities (although it may take months or years). In some cases, remissions and relapse may occur. The prognosis is improved when the onset of the disorder is after age 6 and when speech therapy is started early. Seizures generally disappear by adulthood. (Source: excerpt from NINDS Landau-Kleffner Syndrome Information Page: NINDS)

What causes Landau-Kleffner Syndrome?

Causes of Landau-Kleffner Syndrome: see causes of Landau-Kleffner Syndrome

What are the symptoms of Landau-Kleffner Syndrome?

Symptoms of Landau-Kleffner Syndrome: see symptoms of Landau-Kleffner Syndrome

Complications of Landau-Kleffner Syndrome: see complications of Landau-Kleffner Syndrome

Landau-Kleffner Syndrome: Testing

Diagnostic testing: see tests for Landau-Kleffner Syndrome.

Misdiagnosis: see misdiagnosis and Landau-Kleffner Syndrome.

How is it treated?

Doctors and Medical Specialists for Landau-Kleffner Syndrome: Medical Geneticist, Neurologist ; see also doctors and medical specialists for Landau-Kleffner Syndrome.
Treatments for Landau-Kleffner Syndrome: see treatments for Landau-Kleffner Syndrome
Research for Landau-Kleffner Syndrome: see research for Landau-Kleffner Syndrome

Organs Affected by Landau-Kleffner Syndrome:

Organs and body systems related to Landau-Kleffner Syndrome include:

Name and Aliases of Landau-Kleffner Syndrome

Main name of condition: Landau-Kleffner Syndrome

Other names or spellings for Landau-Kleffner Syndrome:

Acquired Epileptiform Aphasia, LKS, Aphasia-epilepsy, acquired, Acquired aphasia with convulsive disorder

Acquired epileptic aphasia Source - Diseases Database

Acquired aphasia with convulsive disorder, LKS, Acquired aphasia with convulsive disorder
Source - Office of Rare Diseases (ORD) of the National Institutes of Health (NIH)

Landau-Kleffner Syndrome: Related Conditions

Research the causes of these diseases that are similar to, or related to, Landau-Kleffner Syndrome:


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