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Glossary for Malignant hyperthermia susceptibility type 1

  • Death: The cessation of life
  • Drug-related conditions: Medical conditions related to drug usage, including adverse reactions, intoxication, and overdose.
  • Genetic Disease: Any disease that is handed down to oneself through the chromosomes of ones parents
  • Hospital or surgery-related conditions: Medical conditions related to hospital stays or caused by surgery.
  • Malignant hyperthermia susceptibility type 2: A rare, potential lethal disorder that is triggered by general anesthetic or certain muscle relaxant drugs. On exposure to the drugs, muscle metabolism is severely disrupted and the body is unable to control its temperature which can lead to death without treatment. The chromosomal defect for type 2 is located at 17q11.2-q24.
  • Metabolic acidosis: Metabolic acidosis is a process which if unchecked leads to acidemia (i.e. blood pH is low (less than 7.35) due to increased production of H+ by the body or the inability of the body to form bicarbonate (HCO3-) in the kidney.
  • Muscle rigidity: The occurrence of resistance to passively moving a muscle
  • Poisoning, overdose or adverse reactions: Medical conditions related to poisons, drug overdosage, or drug adverse reactions.
  • Tachycardia: Excessively rapid heart beat.


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