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Mastocytosis: Introduction

Mastocytosis: Mastocytosis is a group of disorders in both children and adults caused by the presence of too many mast cells in a person's body. Located in ... more about Mastocytosis.

Mastocytosis: A disorder where excessive amounts of mast cells proliferate in organs such as the skin, liver, bone, spleen and gastrointestinal tract. Mast cells occur in connective tissue and defend the body against disease by releasing histamine to stimulate the immune system. More detailed information about the symptoms, causes, and treatments of Mastocytosis is available below.

Symptoms of Mastocytosis

Treatments for Mastocytosis

  • Usually no treatment is required and the skin bumps disappear with age. Problematic causes may require theuse of antihistamine medication to manage the itching and other cases may require the bumps to be surgically removed
  • more treatments...»

Home Diagnostic Testing

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Wrongly Diagnosed with Mastocytosis?

Mastocytosis: Related Patient Stories

Types of Mastocytosis

Mastocytosis: Complications

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Causes of Mastocytosis

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Disease Topics Related To Mastocytosis

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Prognosis for Mastocytosis

Prognosis for Mastocytosis: The condition is generally harmless but may cause discomfort.

Research about Mastocytosis

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Clinical Trials for Mastocytosis

The US based website lists information on both federally and privately supported clinical trials using human volunteers.

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Statistics for Mastocytosis

Mastocytosis: Broader Related Topics

Mastocytosis Message Boards

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Article Excerpts about Mastocytosis

Mastocytosis is a group of disorders in both children and adults caused by the presence of too many mast cells in a person's body. Located in skin, the linings of the stomach and intestine, as well as other sites, mast cells may play an important role in helping defend these tissues from disease. By releasing chemical "alarms" such as histamine, mast cells attract other key players of the immune defense system to areas of the body where they are needed. (Source: excerpt from Mastocytosis, NIAID Fact Sheet: NIAID)

Definitions of Mastocytosis:

A heterogeneous group of disorders characterized by the abnormal growth and accumulation of mast cells in one or more organ systems. Recent data suggest that most variants of mastocytosis are clonal disorders. (WHO, 2001) -- 2003 - (Source - Diseases Database)

Mastocytosis is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that Mastocytosis, or a subtype of Mastocytosis, affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)


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