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Treatments for Membranoproliferative glomerulonephritis (type 2)

Treatment List for Membranoproliferative glomerulonephritis (type 2)

The list of treatments mentioned in various sources for Membranoproliferative glomerulonephritis (type 2) includes the following list. Always seek professional medical advice about any treatment or change in treatment plans.

  • Treatment of membranoproliferative glomerulonephritis is dependant upon the severity of renal impairment, as well as the age and comorbidities of the patient. Treatments include:
    • Corticosteroids and immunosuppressants - may have a role in autoimmune disease
    • Antihypertensives - for management of high blood pressure, both in the acute and chronic phase
    • Fluid restriction - for significant oedema
    • Diuretics - for fluid overload
    • Avoidance of medications that may contribute to further renal damage - NSAID's, IV contrast
    • Renal dialysis - may be required for acute severe renal failure, or chronic renal failure
    • Dietary management depending on the severity of renal impairment
      • Protein management - depends on the amount of protein lost in the urine and the degree of renal failure
      • Salt and water restriction as necessary to manage fluid overload
      • Phosphate restriction
      • Potassium restriction as necessary
    • Management of chronic renal failure as required
      • Erythropoietin agonists - for management of anaemia associated with chronic renal failure
      • Phosphate binders - for management of hyperphosphatemia in chronic renal failure
      • Calcium supplements - for hypocalcaemia associated with chronic renal failure
      • Calcitriol and other Vitamin D supplements - for hypocalcaemia and hyperparathyroidism associated with chronic renal failure
      • Sodium bicarbonate - for acid-base disturbance
      • Renal dialysis - used when there are manifestations of uraemia and the GFR is < 10mL/min
      • Renal transplantation

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