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Mobius syndrome is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that Mobius syndrome, or a subtype of Mobius syndrome, affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)
Ophanet, a consortium of European partners, currently defines a condition rare when it affects 1 person per 2,000. They list Mobius syndrome as a "rare disease".
Source - Orphanet
Miller, M, et. al.
Mobius and Mobius-like Syndrome. Journal of Pediatric Ophthalmology and Strabismus, 26:4; 176-188 (July-August 1989).
Raroque, H, et. al.
Mobius Syndrome and Transposition of the Great Vessels. Neurology, 38; 1894-1895 (1988).
Cohen, S, and Thompson, J.
Variants of Mobius Syndrome and Central Neurologic Impairment: Lindeman Procedure in Children. Annals of Otology, Rhinology, and Laryngology, 96; 93-100 (1987). (Source: excerpt from NINDS Mobius Syndrome Information Page: NINDS)
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