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Diseases » Morphea » Glossary

Glossary for Morphea

  • Connective tissue disorders: Any condition affecting connective tissues.
  • Decreased pigmentation: A decrease in the melanocytic composition of the skin.
  • Hypomelanotic disorder: Lack of pigmentation
  • Lichen sclerosis et atrophicus: A chronic skin disease characterized by shiny, white atrophic skin patches which tend to occur on the neck, genital areas, around the anus, under the breasts and in body folds.
  • Localized Scleroderma: A condition characterized by localized hardening of the skin
  • Oral submucous fibrosis: A rare disorder involving inflammation and progressive fibrosis of tissues inside the mouth. The condition starts with redness, blistering and ulceration inside the mouth that is eventually replaced with stiff fibrous tissue as it heals. The inside of the mouth can become stiff and hinder oral functions such as eating, speaking and even opening the mouth. Even the pharynx may occasionally be involved. The condition can become cancerous. The disorder is often associated with chewing betel nuts in Asian and Indian areas.
  • Pruritus: The sensation of itch
  • Scleroderma: A rare, progressive connective tissue disorder involving thickening and hardening of the skin and connective tissue. There are a number of forms of scleroderma with some forms being systemic (involving internal organs).
  • Scleroderma, systemic: A rare autoimmune connective tissue disease where the body attacks parts of the body and causes scarring and thickness of the tissue. In the systemic form, the skin and organs are involved.
  • Skin conditions: Any condition that affects the skin
  • Velocardiofacial syndrome: A genetic disorder which can present with a wide range of phenotypic manifestations which has lead to a number of different names being assigned to the various presentations e.g. DiGeorge Syndrome and Cayler Anomaly Face Syndrome. There are nearly 200 different symptoms that can occur and the severity of the condition is also highly variable depending on the nature and severity of the symptoms that are present.


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