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Glossary for Myelofibrosis-osteosclerosis

  • Anemia: Reduced ability of blood to carry oxygen from various possible causes.
  • Ascites: Fluid accumulation in abdominal cavity
  • Blood conditions: Conditions that affect the blood
  • Bone Marrow Conditions: Medical conditions affecting the bone marrow
  • Bone conditions: Conditions that affect the bones
  • Chronic Idiopathic Myelofibrosis: The bone marrow is consists of tissues which make blood cells and fibrous tissue supports these tissues that make the blood cells. In chronic idiopathic myelofibrosis, abnormal cells and fibres build up inside the bone marrow resulting in the production of fewer normal blood cells.
  • Dizziness: Feelings of lightheadedness or giddiness.
  • Fatigue: Excessive tiredness or weakness.
  • Greenberg dysplasia: A very rare form of short-limbed dwarfism.
  • Headache: In medicine a headache or cephalalgia is a symptom of a number of different conditions of the head and sometimes neck. Some of the causes are benign while others are medical emergencies. It ranks among the most common pain complaints
  • Hereditary spherocytosis: A rare genetic condition characterized by a defect of the red blood cell membrane. It is characterized by abnormally-shaped red blood cells which are spherical rather than doughnut-shaped. The abnormal red blood cells are broken down by the spleen sooner than normal which leads to problems such as anemia. There are various subtypes of the disorder which are distinguished by the origin of the underlying genetic defect.
  • Myelofibrosis: A rare condition where progressive scarring or fibrosis of the bone marrow impairs it's ability to make blood cells causing symptoms such as anemia and liver and spleen enlargement.
  • Myoglobinuria: Myoglobin (muscle protein) in the urine. It is often caused by destruction of muscle tissue for a variety of reasons such as certain drugs, metabolic abnormalities and trauma.
  • No symptoms: The absence of noticable symptoms.
  • Osteosclerosis with ichtyhosis and premature ovarian failure:
  • Paleness: Whitening or pallor of the skin
  • Pleural effusion: Fluid in the pleural spaces.
  • Swollen spleen: Swelling or enlargement of the spleen
  • Weakness: Symptoms causing weakness of the body


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