Treatments for Myoclonus
Treatment List for Myoclonus
The list of treatments mentioned in various sources
includes the following list.
Always seek professional medical advice about any treatment
or change in treatment plans.
Myoclonus: Is the Diagnosis Correct?
The first step in getting correct treatment is
to get a correct diagnosis.
Differential diagnosis list for Myoclonus may include:
Hidden causes of Myoclonus may be incorrectly diagnosed:
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Hospital statistics for Myoclonus:
These medical statistics relate to hospitals, hospitalization and Myoclonus:
- 0.004% (471) of hospital consultant episodes were for myoclonus in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
- 86% of hospital consultant episodes for myoclonus required hospital admission in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
- 44% of hospital consultant episodes for myoclonus were for men in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
- 56% of hospital consultant episodes for myoclonus were for women in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
- more hospital information...»
Discussion of treatments for Myoclonus:
NINDS Myoclonus Information Page: NINDS (Excerpt)
Treatment for myoclonus consists of medications that may
help reduce symptoms. Many of these drugs, which include barbiturates,
clonazepam, phenytoin, primidone, and sodium valproate, are also used to
treat epilepsy. The complex origins of myoclonus may require the use of
multiple drugs for effective treatment.
(Source: excerpt from NINDS Myoclonus Information Page: NINDS)
Myoclonus Fact Sheet: NINDS (Excerpt)
Treatment of myoclonus focuses on medications that may help reduce
symptoms. The drug of first choice to treat myoclonus, especially certain
types of action myoclonus, is clonazepam, a type of tranquilizer. Dosages
of clonazepam usually are increased gradually until the patient improves
or side effects become harmful. Drowsiness and loss of coordination are
common side effects. The beneficial effects of clonazepam may diminish
over time if the patient develops a tolerance for the drug.
Many of the drugs used for myoclonus, such as barbiturates, phenytoin,
and primidone, are also used to treat epilepsy. Barbiturates slow down the
central nervous system and cause tranquilizing or antiseizure effects.
Phenytoin and primidone are effective antiepileptic drugs, although
phenytoin can cause liver failure or have other harmful long-term effects
in patients with PME. Sodium valproate is an alternative therapy for
myoclonus and can be used either alone or in combination with clonazepam.
Although clonazepam and/or sodium valproate are effective in the majority
of patients with myoclonus, some people have adverse reactions to these
Some studies have shown that doses of 5-hydroxytryptophan (5-HTP), a
building block of serotonin, leads to improvement in patients with some
types of action myoclonus and PME. However, other studies indicate that
5-HTP therapy is not effective in all people with myoclonus, and, in fact,
may worsen the condition in some patients. These differences in the effect
of 5-HTP on patients with myoclonus have not yet been explained, but they
may offer important clues to underlying abnormalities in serotonin
The complex origins of myoclonus may require the use of multiple drugs
for effective treatment. Although some drugs have a limited effect when
used individually, they may have a greater effect when used with drugs
that act on different pathways or mechanisms in the brain. By combining
several of these drugs, scientists hope to achieve greater control of
myoclonic symptoms. Some drugs currently being studied in different
combinations include clonazepam, sodium valproate, piracetam, and
primidone. Hormonal therapy also may improve responses to antimyoclonic
drugs in some people. (Source: excerpt from Myoclonus Fact Sheet: NINDS)
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