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Dictionary » 5-Azacytidine


Introduction: 5-Azacytidine

Description of 5-Azacytidine

5-Azacytidine (medical condition): Experimental studies on mice and rats indicate that the use of 5...more »

See also:

5-Azacytidine -- Teratogenic Agent:
  »Introduction: 5-Azacytidine -- Teratogenic Agent
  »Symptoms of 5-Azacytidine -- Teratogenic Agent

5-Azacytidine: A pyrimidine nucleoside analogue of cytidine with antineoplastic activity. Azacitidine is incorporated into DNA, where it reversibly inhibits DNA methyltransferase, thereby blocking DNA methylation. Hypomethylation of DNA by azacitidine may activate tumor suppressor genes silenced by hypermethylation, resulting in an antitumor effect. This agent is also incorporated into RNA, thereby disrupting normal RNA function and impairing tRNA cytosine-5-methyltransferase activity. (NCI04)
Source: Diseases Database

5-Azacytidine: Related Topics

These medical condition or symptom topics may be relevant to medical information for 5-Azacytidine:

5-Azacytidine as a Disease

5-Azacytidine: Another name for 5-Azacytidine -- Teratogenic Agent (or close medical condition association).
  »Introduction: 5-Azacytidine -- Teratogenic Agent
  »Symptoms of 5-Azacytidine -- Teratogenic Agent

5-Azacytidine: Related Diseases

5-Azacytidine: 5-Azacytidine is listed as a type of (or associated with) the following medical conditions in our database:

Symptoms of 5-Azacytidine (5-Azacytidine -- Teratogenic Agent)

Some of the symptoms of 5-Azacytidine incude:

  • Exencephaly in mice
  • Exencephaly in rats
  • Encephalocele in rats
  • Eye defects in rats

Terms associated with 5-Azacytidine:

Terms Similar to 5-Azacytidine:

Source: Diseases Database

External links related to: 5-Azacytidine

Source: Diseases Database

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More Medical Dictionary Topics

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  • Pubocapsular ligament
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  • Pubococcygeal
  • Pubococcygeal muscle
  • Pubococcygeus (muscle)
  • Pubofemoral
  • Pubofemoral ligament
  • Puboperinealis (muscle)

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