Have a symptom?
See what questions
a doctor would ask.
Dictionary » Antineoplastic Agents, Alkylating

Antineoplastic Agents, Alkylating

Introduction: Antineoplastic Agents, Alkylating

Description of Antineoplastic Agents, Alkylating

Antineoplastic Agents, Alkylating: A class of drugs that differs from other alkylating agents used clinically in that they are monofunctional and thus unable to cross-link cellular macromolecules. Among their common properties are a requirement for metabolic activation to intermediates with antitumor efficacy and the presence in their chemical structures of N-methyl groups, that after metabolism, can covalently modify cellular DNA. The precise mechanisms by which each of these drugs acts to kill tumor cells are not completely understood. (From AMA, Drug Evaluations Annual, 1994, p2026).
Source: MeSH 2007

Antineoplastic Agents, Alkylating: Related Topics

These medical condition or symptom topics may be relevant to medical information for Antineoplastic Agents, Alkylating:

Interesting Medical Articles:

Medical dictionaries:

More Medical Dictionary Topics

  • Other specified noninflammatory disorders of cervix
  • Other specified noninflammatory disorders of vagina
  • Other specified noninflammatory disorders of vulva and perineum
  • Other specified nonpsychotic mental disorders following organic brain damage
  • Other specified nonteratogenic anomalies
  • Other specified obstetrical trauma
  • Other specified obstetrical trauma, antepartum
  • Other specified obstetrical trauma, delivered, with postpartum condition or complication
  • Other specified obstetrical trauma, postpartum
  • Other specified obstetrical trauma, unspecified as to episode of care
  • Other specified obstetrical trauma, with delivery
  • Other specified open wounds of ocular adnexa
  • Other specified organ or tissue replaced by transplant
  • Other specified osteopathic manipulative treatment
  • Other specified paralytic syndrome

    Find out more

    Search to find out more about Antineoplastic Agents, Alkylating:

    powered by

    By using this site you agree to our Terms of Use. Information provided on this site is for informational purposes only; it is not intended as a substitute for advice from your own medical team. The information on this site is not to be used for diagnosing or treating any health concerns you may have - please contact your physician or health care professional for all your medical needs. Please see our Terms of Use.

    Home | Symptoms | Diseases | Diagnosis | Videos | Tools | Forum | About Us | Terms of Use | Privacy Policy | Site Map | Advertise