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Dictionary » Aromatase inhibitors

Aromatase inhibitors

Introduction: Aromatase inhibitors

Description of Aromatase inhibitors

Aromatase inhibitors: An agent that blocks the function of the enzyme aromatase with antineoplastic activity. Aromatase inhibitors belong to two classes: Type I steroidal drugs are androgen substrate analogues that bind competitively but irreversibly to the enzyme. Type II nonsteroidal inhibitors fit into the substrate binding site and bind reversibly to the enzyme. Present in many tissues, aromatases are heme-containing enzymes that catalyze the adrenal conversion of cholesterol to pregnenolone and the peripheral conversion (aromatization) of androgenic precursors to estrogens. (NCI04)
Source: Diseases Database

Aromatase inhibitors: Compounds that inhibit AROMATASE in order to reduce production of estrogenic steroid hormones.
Source: MeSH 2007

Aromatase inhibitors: Related Topics

These medical condition or symptom topics may be relevant to medical information for Aromatase inhibitors:

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Source: Diseases Database

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