Have a symptom?
See what questions
a doctor would ask.
Dictionary » Asparaginase


Introduction: Asparaginase

Description of Asparaginase

Asparaginase: antineoplastic drug (trade name Elspar) sometimes used to treat lymphoblastic leukemia.
Source: WordNet 2.1

Asparaginase: An enzyme isolated from the bacterium Escherichia coli or the bacterium Erwinia carotovora. Asparagine is critical to protein synthesis in leukemic cells, which cannot synthesize this amino acid due to the absence of the enzyme asparagine synthase. Asparaginase hydrolyzes L-asparagine to L-aspartic acid and ammonia, thereby depleting leukemic cells of asparagine and blocking protein synthesis and tumor cell proliferation, especially in the G1 phase of the cell cycle. This agent also induces apoptosis in tumor cells. The E. carotovora-derived form of asparaginase is typically reserved for cases of hypersensitivity. (NCI04)
Source: Diseases Database

Asparaginase: EC
Source: CRISP

Asparaginase: A hydrolase enzyme that converts L-asparagine and water to L-aspartate and NH3. EC
Source: MeSH 2007

Asparaginase: Related Topics

These medical condition or symptom topics may be relevant to medical information for Asparaginase:

Drug name confusion

Because many drug names share similar spellings or sound almost identical when spoken, it is possible to mistake the name of a particular medication. Other drugs that are sometimes confused with Asparaginase include:

Terms associated with Asparaginase:

Terms Similar to Asparaginase:

Source: Diseases Database

  • Elspar

Source - WordNet 2.1

Broader terms for Asparaginase

Source - MeSH 2007

Source - CRISP

Source - WordNet 2.1

The term Asparaginase can be used for:

Source: CRISP

Hierarchical classifications of Asparaginase

The following list attempts to classify Asparaginase into categories where each line is subset of the next.

WordNet 2.1

  • antineoplastic,antineoplastic drug,cancer drug
  • cytotoxic drug
  • medicament,medication,medicinal drug,medicine
  • drug
  • agent
  • causal agency,causal agent,cause
  • entity

Source: WordNet 2.1

MeSH 2007 Hierarchy:

External links related to: Asparaginase

Source: Diseases Database

Interesting Medical Articles:

Medical dictionaries:

More Medical Dictionary Topics

  • Hirschsprung disease with ulnar polydactyly, polysyndactyly of big toes, and ventricular septal defect
  • Hirschsprung disease, deafness and polydactyly
  • Hirschsprung nail hypoplasia dysmorphism
  • Hirschsprung's disease
  • Hirschsprung's disease and other congenital functional disorders of colon
  • Hirschsprung's disease associated with congenital heart malformation, broad big toes, and ulnar polydactyly
  • Hirschsprung's disease associated with ulnar polydactyly, polysyndactyly of big toes and ventricular septal defect
  • Hirschsprung's disease, hypoplastic nails, and dysmorphic facial features
  • Hirschsprung's disease, hypoplastic nails, and minor dysmorphic features
  • Hirsuitism
  • Hirsute
  • Hirsuties
  • Hirsutism
  • Hirsutism congenital gingival hyperplasia
  • Hirsutism skeletal dysplasia mental retardation

    Find out more

    Search to find out more about Asparaginase:

    powered by

    By using this site you agree to our Terms of Use. Information provided on this site is for informational purposes only; it is not intended as a substitute for advice from your own medical team. The information on this site is not to be used for diagnosing or treating any health concerns you may have - please contact your physician or health care professional for all your medical needs. Please see our Terms of Use.

    Home | Symptoms | Diseases | Diagnosis | Videos | Tools | Forum | About Us | Terms of Use | Privacy Policy | Site Map | Advertise