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Dictionary » Calcium Channels, L-Type

Calcium Channels, L-Type

Introduction: Calcium Channels, L-Type

Description of Calcium Channels, L-Type

Calcium Channels, L-Type: Long-lasting voltage-gated CALCIUM CHANNELS found in both excitable and nonexcitable tissue. They are responsible for normal myocardial and vascular smooth muscle contractility. Five subunits (alpha-1, alpha-2, beta, gamma, and delta) make up the L-type channel. The alpha-1 subunit is the binding site for calcium-based antagonists. Dihydropyridine-based calcium antagonists are used as markers for these binding sites.
Source: MeSH 2007

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